Evidence map›Paper›PMID 29214782›Full record

ArticleYonsei medical journal2018

Effect of Family History of Diabetes on Hemoglobin A1c Levels among Individuals with and without Diabetes: The Dong-gu Study.

Young Hoon Lee, Min Ho Shin, Hae Sung Nam, Kyeong Soo Park, Seong Woo Choi, So Yeon Ryu, Sun Seog Kweon

Open access · goldAbstract read
In one paragraph

Article in Yonsei medical journal, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
0.7field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 21 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 5 institutions in 1 country.

Young Hoon LeeDepartment of Preventive Medicine & Institute of Wonkwang Medical Science, Wonkwang University School of Medicine, Iksan, Korea.ORCID https://orcid.org/0000-0003-1367-025X
Min Ho ShinDepartment of Preventive Medicine, Chonnam National University Medical School, Gwangju, Korea.
Hae Sung NamDepartment of Preventive Medicine, Chungnam National University College of Medicine, Daejeon, Korea.
Kyeong Soo ParkDepartment of Preventive Medicine, Seonam University College of Medicine, Namwon, Korea.
Seong Woo ChoiDepartment of Preventive Medicine, Chosun University Medical School, Gwangju, Korea.
So Yeon RyuDepartment of Preventive Medicine, Chosun University Medical School, Gwangju, Korea.
Sun Seog KweonDepartment of Preventive Medicine, Chonnam National University Medical School, Gwangju, Korea.ORCID https://orcid.org/0000-0003-2378-8550
Chonnam National University Hospital · KRChosun University · KRChungnam National University · KRSeonam University · KRWonkwang University · KR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeWe investigated associations between family history of diabetes (FHD) and hemoglobin A1c (HbA1c) level, among people with and without diabetes. MATERIALS AND

methodsIn total, 7031 people without diabetes and 1918 people with diabetes who participated in the Dong-gu Study were included. Data on FHD in first-degree relatives (father, mother, and siblings) were obtained. Elevated HbA1c levels in people without diabetes and high HbA1c levels in people with diabetes were defined as the highest quintiles of HbA1c ≥5.9% and ≥7.9%, respectively.

resultsIn people without diabetes, the odds of elevated HbA1c levels [odds ratio (OR) 1.34, 95% confidence interval (CI) 1.13-1.59] were significantly greater in people with any FHD than in those without. Specifically, the odds of elevated HbA1c levels in people without diabetes with an FHD involving siblings were greater than in those without an FHD involving siblings. Additionally, in people with diabetes, the odds of high HbA1c levels (OR 1.33, 95% CI 1.02-1.72) were greater in people with any FHD than in those without such history. Moreover, people with diabetes with maternal FHD had increased odds of high HbA1c levels.

conclusionFHD was associated not only with high HbA1c levels in people with diabetes, but also with elevated HbA1c levels in people without diabetes.

Indexed as

AgedBlood GlucoseDiabetes MellitusFamilyFemaleGlycated HemoglobinHumansLogistic ModelsMaleMiddle AgedOdds RatioPrevalenceRisk FactorsBlood GlucoseGlycated Hemoglobinblood glucosediabetes mellitusFamily historyHbA1c

Identifiers

PMID29214782
PMCPMC5725370
OpenAlexW2775042933

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.