Evidence map›Paper›PMID 29214468›Full record

ArticlePsychopharmacology2018

Effects of acute alcohol and driving complexity in older and younger adults.

Julianne L Price, Ben Lewis, Jeff Boissoneault, Ian R Frazier, Sara Jo Nixon

Abstract read
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In one paragraph

Article in Psychopharmacology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Trial
  2. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Julianne L PriceDepartment of Psychiatry, University of Florida, PO Box 100256, Gainesville, FL, 32610, USA. juliannelp@ufl.edu.ORCID 0000-0001-7106-1386
Ben LewisDepartment of Psychiatry, University of Florida, PO Box 100256, Gainesville, FL, 32610, USA.
Jeff BoissoneaultDepartment of Clinical and Health Psychology, University of Florida, PO Box 100256, Gainesville, FL, 32610, USA.
Ian R FrazierDepartment of Psychology, University of Florida, PO Box 100256, Gainesville, FL, 32610, USA.
Sara Jo NixonDepartment of Psychiatry, University of Florida, PO Box 100256, Gainesville, FL, 32610, USA.

Funding

Neurocognition and Performance after Moderate Drinking in Older AdultsR01AA019802 · NIAAA · UNIVERSITY OF FLORIDA · PI NIXON, SARA JO · 2010 to 2012
$1.4M
NIAAA NIH HHS F31AA0919862NIAAA NIH HHS R01 AA019802
6 · The paper itself

Abstract

rationaleOur previous work demonstrated differential neurobehavioral effects of low-dose alcohol consumption on older and younger adults in a driving simulator. However, the ability to enhance or suppress a response in such context has yet to be examined.

objectivesThe current study contrasted older and younger drivers' responses to specific stimuli (i.e., relevant, irrelevant) in scenarios of differing complexity following low-dose acute alcohol administration.

methodsHealthy older (55-70) and younger (25-35) adults completed two driving scenarios (i.e., country and metropolis) both before and after consuming beverages targeted to reach peak BrACs of 0.00, 0.04, or 0.065%. Throughout the simulation, participants encountered relevant stimuli (e.g., pedestrians walking into the street) and irrelevant stimuli (e.g., pedestrians walking parallel). Peak deceleration, range of steering, and distance until brake application were assessed within a 450-ft window preceding each stimulus.

resultsFollowing low-dose alcohol consumption, older adults shifted from a strategy using both deceleration and steering to relying solely on deceleration in responding to relevant stimuli in the country. Older adults under both low and moderate alcohol conditions displayed an inability to withhold responses to irrelevant stimuli in the metropolis.

conclusionThese findings are consistent with our prior work showing differential effects of low-dose alcohol on older, relative to younger, adults. The interactive effects of age and alcohol, however, depend on stimulus type and environmental complexity. Continued investigation of neurobehavioral mechanisms in ecologically valid paradigms is necessary for understanding the implications of the combined impairing effects of alcohol and older age.

Indexed as

AdultAgedAge FactorsAgingAlcohol DrinkingAlcohol-Related DisordersAutomobile DrivingCentral Nervous System DepressantsEthanolFemaleHumansMaleMiddle AgedPsychomotor PerformanceCentral Nervous System DepressantsEthanolAgingAlcoholBreath alcohol concentrations (BrACs)Driving

Identifiers

PMID29214468
PMCPMC5823740

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.