Evidence map›Paper›PMID 29214461›Full record

Trial reportEuropean journal of applied physiology2018

Co-ingestion of protein or a protein hydrolysate with carbohydrate enhances anabolic signaling, but not glycogen resynthesis, following recovery from prolonged aerobic exercise in trained cyclists.

Karl E Cogan, Mark Evans, Enzo Iuliano, Audrey Melvin, Davide Susta, Karl Neff, Giuseppe De Vito, Brendan Egan

Abstract readRandomized Controlled Trial
PubMed Publisher
In one paragraph

Trial report in European journal of applied physiology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed, 1 pooled it
0.4field-weighted citation impact, top 39% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 1 synthesis or guideline pooled it, 28 citations in OpenAlex.

  1. Pooled it
  2. Trial
  3. Trial
  4. Review
  5. Review
  6. Review
  7. Review
  8. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 2 countries.

Karl E CoganInstitute for Sport and Health, University College Dublin, Dublin, Ireland.
Mark EvansSchool of Health and Human Performance, Dublin City University, Glasnevin, Dublin 9, Ireland.
Enzo IulianoInstitute for Sport and Health, University College Dublin, Dublin, Ireland.
Audrey MelvinDiabetes Complications Research Centre, Conway Institute of Biomolecular and Biomedical Science, University College Dublin, Dublin, Ireland.
Davide SustaSchool of Health and Human Performance, Dublin City University, Glasnevin, Dublin 9, Ireland.
Karl NeffDiabetes Complications Research Centre, Conway Institute of Biomolecular and Biomedical Science, University College Dublin, Dublin, Ireland.
Giuseppe De VitoInstitute for Sport and Health, University College Dublin, Dublin, Ireland.
Brendan EganInstitute for Sport and Health, University College Dublin, Dublin, Ireland. brendan.egan@dcu.ie.ORCID http://orcid.org/0000-0001-8327-9016
University College Dublin · IEDublin City University · IEFood for Health Ireland · IE

Funding

Enterprise Ireland TC2013001
6 · The paper itself

Abstract

purposeThe effect of carbohydrate (CHO), or CHO supplemented with either sodium caseinate protein (CHO-C) or a sodium caseinate protein hydrolysate (CHO-H) on the recovery of skeletal muscle glycogen and anabolic signaling following prolonged aerobic exercise was determined in trained male cyclists [n = 11, mean ± SEM age 28.8 ± 2.3 years; body mass (BM) 75.0 ± 2.3 kg; VO

methodsOn three separate occasions, participants cycled for 2 h at ~ 70% VO

resultsDespite an augmented insulin response following CHO-H ingestion, there was no significant difference in skeletal muscle glycogen resynthesis following recovery between trials. CHO-C and CHO-H co-ingestion significantly increased phospho-mTOR Ser

conclusionSupplementing CHO with intact sodium caseinate or an insulinotropic hydrolysate derivative augmented intracellular signaling associated with skeletal muscle protein synthesis following prolonged aerobic exercise.

Indexed as

ExerciseRecovery of FunctionAdultCaseinsDietary CarbohydratesGlycogenHumansMaleMuscle FatigueMuscle, SkeletalSignal TransductionCaseinsDietary CarbohydratesGlycogenCyclingNutritionProtein synthesisSodium caseinateSupplementation

Identifiers

PMID29214461
OpenAlexW2775303915

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.