ReviewWorld journal of microbiology & biotechnology2017
Biological production of L-malate: recent advances and future prospects.
Review in World journal of microbiology & biotechnology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
8 citing papers in PubMed, 29 citations in OpenAlex.
- Combination model for freshness prediction of pork using VIS/NIR hyperspectral imaging with chemometrics.Animal bioscience · 2025Article
- Oral administration of butylated hydroxytoluene induces neuroprotection in a streptozotocin-induced rat Alzheimer's disease model via inhibition of neuronal ferroptosis.Molecular medicine (Cambridge, Mass.) · 2024Article
- Energy recovery from syngas and pyrolysis wastewaters with anaerobic mixed cultures.Bioresources and bioprocessing · 2024Article
- Recent advances in producing food additive L-malate: Chassis, substrate, pathway, fermentation regulation and application.Microbial biotechnology · 2023Review
- Identification of Possible Salivary Metabolic Biomarkers and Altered Metabolic Pathways in South American Patients Diagnosed with Oral Squamous Cell Carcinoma.Metabolites · 2021Article
- Fumarase FromFrontiers in microbiology · 2020Article
- Growing a circular economy with fungal biotechnology: a white paper.Fungal biology and biotechnology · 2020Review
- Engineering energetically efficient transport of dicarboxylic acids in yeastProceedings of the National Academy of Sciences of the United States of America · 2019Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 2 institutions in 2 countries.
Funding
Abstract
As intermediates in the TCA cycle, L-malate and its derivatives have been widely applied in the food, pharmaceutical, agriculture, and bio-based material industries. In recent years, biological routes have been regarded as very promising approaches as cost-effective ways to L-malate production from low-priced raw materials. In this mini-review, we provide a comprehensive overview of current developments of L-malate production using both biocatalysis and microbial fermentation. Biocatalysis is enzymatic transformation of fumarate to L-malate, here, the source of enzymes, catalytic conditions, and enzymatic molecular modification may be concluded. For microbial fermentation, the types of microorganisms, genetic characteristics, biosynthetic pathways, metabolic engineering strategies, fermentation substrates, and optimization of cultivation conditions have been discussed and compared. Furthermore, the combination of enzyme and metabolic engineering has also been summarized. In future, we also expect that novel biological approaches using industrially relevant strains and renewable raw materials can overcome the technical challenges involved in cost-efficient L-malate production.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.