Evidence map›Paper›PMID 29214148›Full record

ArticleFrontiers in oncology2017

Comparison of Functional Outcome after Extended versus Super-Extended Pelvic Lymph Node Dissection during Radical Prostatectomy in High-Risk Localized Prostate Cancer.

Heikki Seikkula, Pieter Janssen, Manuela Tutolo, Lorenzo Tosco, Antonino Battaglia, Lisa Moris, Thomas Van den Broeck, Maarten Albersen, Gert De Meerleer, Hendrik Van Poppel and 2 more

Open access · goldAbstract read
In one paragraph

Article in Frontiers in oncology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
1.0field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 11 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 2 institutions in 2 countries.

Heikki SeikkulaDepartment of Urology, Central Finland Hospital District, Jyväskylä, Finland.
Pieter JanssenDepartment of Urology, University Hospitals Leuven, Leuven, Belgium.
Manuela TutoloDepartment of Urology, University Hospitals Leuven, Leuven, Belgium.
Lorenzo ToscoDepartment of Urology, University Hospitals Leuven, Leuven, Belgium.
Antonino BattagliaDepartment of Urology, University Hospitals Leuven, Leuven, Belgium.
Lisa MorisDepartment of Urology, University Hospitals Leuven, Leuven, Belgium.
Thomas Van den BroeckDepartment of Urology, University Hospitals Leuven, Leuven, Belgium.
Maarten AlbersenDepartment of Urology, University Hospitals Leuven, Leuven, Belgium.
Gert De MeerleerDepartment of Urology, University Hospitals Leuven, Leuven, Belgium.
Hendrik Van PoppelDepartment of Urology, University Hospitals Leuven, Leuven, Belgium.
Wouter EveraertsDepartment of Urology, University Hospitals Leuven, Leuven, Belgium.
Steven JoniauDepartment of Urology, University Hospitals Leuven, Leuven, Belgium.
KU Leuven · BECentral Finland Health Care District · FI

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundUrinary continence and erectile function (EF) are best preserved when meticulous dissection of prostate and nerve sparing technique are used during radical prostatectomy (RP). However, extent of lymph node dissection (LND) may also adversely affect functional results.

objectiveTo determine whether performing a super-extended LND (seLND) has a significant effect on recovery of urinary continence and EF after RP. DESIGN SETTING AND

participantsAll patients who underwent RP from January 2007 until December 2013 were handed questionnaires assessing continence and EF. All patients in whom at least an extended LND (eLND) was performed were selected. This search yielded 526 patients. 172 of these patients had filed out 2 or more questionnaires and were included in our analysis. OUTCOME MEASUREMENTS AND STATISTICAL ANALYSIS: All questionnaires were reviewed. We used Kaplan-Meier analyses and multivariate Cox analysis to assess the difference in recovery of continence and EF over time for eLND/seLND. Primary endpoints were full recovery of continence (no loss of urine) and full recovery of EF (successful intercourse possible). Patients who did not reach the endpoint when the last questionnaire was filled out were censored at that time. Median follow-up was 12.43 months for continence, and 18.97 months for EF. RESULTS AND LIMITATIONS: Patients undergoing seLND have a lower chance of regaining both urinary continence [hazard ratio (HR) 0.59, 95% CI 0.39-0.90,

conclusionExtending the LND template beyond the eLND template may cause at least a significant delay in recovery of urinary continence and leads to less recovery of EF.

Indexed as

erectile functionlymph node dissectionprostate cancerradical prostatectomyurinary incontinence

Identifiers

PMID29214148
PMCPMC5702642
OpenAlexW2768851169

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.