Evidence map›Paper›PMID 29214089›Full record

ArticleCase reports in oncological medicine2017

Systemic Treatment of Metastatic Conjunctival Melanoma.

Simão Pinto Torres, Teresa André, Emanuel Gouveia, Lívio Costa, Maria José Passos

Open access · goldAbstract readCase Reports
In one paragraph

Article in Case reports in oncological medicine, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 32 papers.

0numbers the graph read from it
0cells of the map it votes in
32citing papers in PubMed
4.2field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

32 citing papers in PubMed, 56 citations in OpenAlex.

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  5. Subepithelial Lesions of the Ocular Surface: A Review.Current ophthalmology reports · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Simão Pinto TorresDepartment of Medical Oncology, Hospital Professor Doutor Fernando Fonseca E.P.E., 2720-276 Amadora, Portugal.ORCID 0000-0002-1944-474X
Teresa AndréDepartment of Medical Oncology, Instituto Português de Oncologia de Lisboa, Francisco Gentil E.P.E., 1099-023 Lisboa, Portugal.ORCID 0000-0003-4807-1505
Emanuel GouveiaDepartment of Medical Oncology, Instituto Português de Oncologia de Lisboa, Francisco Gentil E.P.E., 1099-023 Lisboa, Portugal.
Lívio CostaDepartment of Ophthalmology, Centro Hospitalar Lisboa Central E.P.E., 1150-199 Lisboa, Portugal.
Maria José PassosDepartment of Medical Oncology, Instituto Português de Oncologia de Lisboa, Francisco Gentil E.P.E., 1099-023 Lisboa, Portugal.
Hospital Prof. Dr. Fernando Fonseca · PTUnidade Local de Saúde de São José · PT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Conjunctival melanoma (CM) is an exceptionally rare tumor, with a propensity for local and distant recurrence, with the lungs, skin, liver, and brain being the most common sites of metastasis. Recent progress in systemic treatments, with checkpoint inhibitors and targeted therapies blocking BRAF and MEK, has redefined the standard of care of advanced unresectable and metastatic melanoma. Although most trials did not include patients with conjunctival melanoma, its close molecular and genetic relationship to cutaneous melanoma might suggest a similar response to these novel agents. The authors describe two uncommon cases of metastatic conjunctival melanomas with distinct genetic profiles and, as such, submitted to different systemic treatments.

Identifiers

PMID29214089
PMCPMC5682064
OpenAlexW2766835177

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.