Trial reportChiropractic & manual therapies2017
Effect of spinal manipulative treatment on cardiovascular autonomic control in patients with acute low back pain.
Trial report in Chiropractic & manual therapies, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers, 4 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
21 citing papers in PubMed, 4 syntheses or guidelines pooled it, 42 citations in OpenAlex.
- Effectiveness of spinal manipulation in influencing the autonomic nervous system - a systematic review and meta-analysis.The Journal of manual & manipulative therapy · 2024Pooled it
- Sham treatment effects in manual therapy trials on back pain patients: a systematic review and pairwise meta-analysis.BMJ open · 2021Pooled it
- Effectiveness of an osteopathic treatment on the autonomic nervous system: a systematic review of the literature.European journal of medical research · 2019Pooled it
- The acute effects of joint manipulative techniques on markers of autonomic nervous system activity: a systematic review and meta-analysis of randomized sham-controlled trials.Chiropractic & manual therapies · 2019Pooled it
- Modulation of Heart Rate Variability following PAP Ion Magnetic Induction Intervention in Subjects with Chronic Musculoskeletal Pain: A Pilot Randomized Controlled Study.International journal of environmental research and public health · 2023Trial
- The effect of spinal manipulative therapy and home stretching exercises on heart rate variability in patients with persistent or recurrent neck pain: a randomized controlled trial.Chiropractic & manual therapies · 2021Trial
- The effect of a single spinal manipulation on cardiovascular autonomic activity and the relationship to pressure pain threshold: a randomized, cross-over, sham-controlled trial.Chiropractic & manual therapies · 2020Trial
- Review
- Do Pain and Autonomic Regulation Share a Common Central Compensatory Pathway? A Meta-Analysis of HRV Metrics in Pain Trials.NeuroSci · 2025Review
- Effect of osteopathic manipulative treatment on pain in palliative care patients: a randomized placebo-controlled clinical trial.Pain reports · 2025Article
- Lumbar Paravertebral Muscle Pain Management Using Kinesitherapy and Electrotherapeutic Modalities.Healthcare (Basel, Switzerland) · 2024Article
- Review
- Is Acute Lower Back Pain Associated with Heart Rate Variability Changes? A Protocol for Systematic Reviews.Healthcare (Basel, Switzerland) · 2024Article
- Does Osteopathic Heart-Focused Palpation Modify Heart Rate Variability in Stressed Participants with Musculoskeletal Pain? A Randomised Controlled Pilot Study.Healthcare (Basel, Switzerland) · 2024Article
- Accuracy and reliability of the optoelectronic plethysmography and the heart rate systems for measuring breathing rates compared with the spirometer.Scientific reports · 2022Article
- Effects of trunk posture on cardiovascular and autonomic nervous systems: A pilot study.Frontiers in physiology · 2022Article
- Exploring expectations and perceptions of different manual therapy techniques in chronic low back pain: a qualitative study.BMC musculoskeletal disorders · 2021Article
- A systematic review and meta-analysis on effect of spinal mobilization and manipulation on cardiovascular responses.Hong Kong physiotherapy journal : official publication of the Hong Kong Physiotherapy Association Limited = Wu li chih liao · 2020Article
- Chiropractic care for hypertension: Review of the literature and study of biological and genetic bases.Acta bio-medica : Atenei Parmensis · 2020Review
- Feasibility and effectiveness of thoracic spine mobilization on sympathetic/parasympathetic balance in a healthy population - a randomized controlled double-blinded pilot study.Archives of physiotherapy · 2019Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: This study aimed to quantify the effect of spinal manipulative treatment (SMT) from an analysis of baroreflex, systolic blood pressure and heart rate variability (HRV) on patients with acute back pain. It was hypothesized that SMT would increase the parasympathetic cardiovascular autonomic control. Methods: Twenty-two patients with acute back pain were randomly divided into two groups: one receiving sham treatment (Sham) and the other receiving SMT. Recordings were completed during the first day and the seventh day, immediately before and after treatment on both days. ECG and systolic blood pressure were continuously recorded to compute cardiovascular variability and baroreflex sensitivity components. The perceived level of pain was measured with the numeric pain scale (NPS) 48 h before, just before and just after each treatment. The NPS ranged from 0 to 100% (peak of pain before treatment). ECG and systolic blood pressure recordings were analyzed in time frequency domain using the Smoothed pseudo Wigner-Ville distribution. Results: Root mean square of the successive differences, high frequency power of the heart rate variability, and high frequency baroreflex sensitivity differences between post and pre tests were higher in the SMT group than in the Sham group ( Conclusions: This seems to be the first study to assess the effect of SMT on both heart rate variability and baroreflex sensitivity in patients with acute back pain. SMT can be seen to provoke an increase in parasympathetic control known to relate to a person's healthy state. Thus, cardiovascular variability analysis may be a useful tool for clinicians to quantify and objectify the beneficial effects of spinal manipulation treatment.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.