Evidence map›Paper›PMID 29214003›Full record

ArticleIranian journal of microbiology2017

No molecular evidence of Borna disease virus among schizophrenia and bipolar disorder patients in Iran.

Somayeh Shatizadeh-Malekshahi, Hamid Reza Ahmadkhaniha, Seyed Jalal Kiani, Ahmad Nejati, Leila Janani, Jila Yavarian

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In one paragraph

Article in Iranian journal of microbiology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact, top 87% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 0 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Somayeh Shatizadeh-MalekshahiVirology Department, School of Public Health, Tehran University of Medical Sciences, Tehran, Iran.
Hamid Reza AhmadkhanihaMental Health Research Center, Department of Psychiatry, Iran Mental Hospital, Iran University of Medical Sciences, Tehran, Iran.
Seyed Jalal KianiVirology Department, School of Public Health, Tehran University of Medical Sciences, Tehran, Iran.
Ahmad NejatiVirology Department, School of Public Health, Tehran University of Medical Sciences, Tehran, Iran.
Leila JananiDepartment of Biostatistics, School of Public Health, Iran University of Medical Sciences, Tehran, Iran.
Jila YavarianVirology Department, School of Public Health, Tehran University of Medical Sciences, Tehran, Iran.
Tehran University of Medical Sciences · IRIran University of Medical Sciences · IR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

BACKGROUND AND

objectivesViruses have been suggested as one of the risk factors for psychiatric disorders. Among infectious agents Borna disease virus (BDV) has been known as a neurotropic virus which is able to cause neurological disorders in different animals. Recently there were controversial findings about BDV association with pathogenesis of human psychotic disorders. MATERIALS AND

methodsHere we performed a nested reverse transcription polymerase chain reaction for detection of BDV P40 RNA in peripheral blood mononuclear cell samples of schizophrenia (SC), bipolar disorder (BD) patients and healthy controls (HCs).

resultsOnly one out of 120 (0.8 %) psychiatric patients and two samples (2.7%) in 75 HCs showed positive results. There were no significant molecular evidence of BDV infection in 120 psychotic patients (60 SC and 60 BD) and 75 matched HCs.

conclusionOur findings showed no association between BDV infection and pathogenesis of these psychiatric disorders. This is an interesting issue given both the as yet un-clarified role of BDV in human mental disorders and addressing patients in the so far under-investigating Middle East era.

Indexed as

Bipolar disorderBorna disease virusIranNested RT-PCRSchizophrenia

Identifiers

PMID29214003
PMCPMC5715276
OpenAlexW2747400149

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.