Executive functions as a potential neurocognitive endophenotype in anxiety disorders: A systematic review considering DSM-IV and DSM-5 diagnostic criteria classification.

Juliana de Lima Muller, Kamilla Irigaray Torquato, Gisele Gus Manfro, Clarissa Marceli Trentini

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Article in Dementia & neuropsychologia. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

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1 · What the graph read from it

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1 citing paper in PubMed.

The clinical characterization of the adult patient with an anxiety or related disorder aimed at personalization of management.World psychiatry : official journal of the World Psychiatric Association (WPA) · 2021
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5 · Who and what money

Authors and funding

4 authors.

Juliana de Lima MullerPsychologist. Doctoral student at the Institute of Psychology, Federal University of Rio Grande do Sul, Porto Alegre RS, Brazil.

Kamilla Irigaray TorquatoStudent of Psychology at the Federal University of Health Sciences of Porto Alegre, Porto Alegre RS, Brazil.

Gisele Gus ManfroPhD, Psychiatrist, Professor at the Department of Psychiatry and on the Post-graduate Program in Medical Sciences: Psychiatry, Federal University of Rio Grande do Sul, Porto Alegre RS, Brazil. Coordinator of the Anxiety Disorders Outpatient unit Program (PROTAN) of the Hospital de Clínicas de Porto Alegre and the Anxiety Disorders Program in Childhood and Adolescence (PROTAIA) of the Federal University of Rio Grande do Sul and Hospital de Clínicas de Porto Alegre, RS, Brazil.

Clarissa Marceli TrentiniPhD, Psychologist, Professor at the Institute of Psychology, Federal University of Rio Grande do Sul, Porto Alegre RS, Brazil. Coordinator of the Núcleo de Estudos em Avaliação Psicológica e Psicopatologia (NEAPP).

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Evidence in the literature indicates that neurocognitive impairments may represent endophenotypes in psychiatric disorders.

objectiveThis study aimed to conduct a systematic review on executive functions as a potential neurocognitive endophenotype in anxiety disorder diagnosis according to the DSM-IV and DSM-5 classifications.

methodsA literature search of the LILACS, Cochrane Library, Index Psi Periódicos Técnico-Científicos, PubMed and PsycInfo databases was conducted, with no time limits. Of the 259 studies found, 14 were included in this review.

resultsOnly studies on obsessive-compulsive disorder (OCD) were found. The executive function components of decision-making, planning, response inhibition, behavioral reversal/alternation, reversal learning and set-shifting/cognitive flexibility were considered to be a neurocognitive endophenotypes in OCD.

conclusionFurther studies on executive functions as a neurocognitive endophenotype in other anxiety disorders are needed since these may have different neurocognitive endophenotypes and require other prevention and treatment approaches.

Indexed as

anxiety disordersendophenotypesexecutive functionneuropsychology

Identifiers

PMID29213974

DOI10.1590/1980-57642015DN93000012

PMCPMC5619371

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