Evidence map›Paper›PMID 29213941›Full record

ArticleDementia & neuropsychologia

Subjective memory complaints associated with depression and cognitive impairment in the elderly: A systematic review.

Allan Gustavo Brigola, Carlene Souza Silva Manzini, Gabriel Brassi Silveira Oliveira, Ana Carolina Ottaviani, Michelli Pacheco Sako, Francisco Assis Carvalho Vale

Abstract read
In one paragraph

Article in Dementia & neuropsychologia. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 40 papers.

0numbers the graph read from it
0cells of the map it votes in
40citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

40 citing papers in PubMed.

  1. The association of self- and interviewer-reported cognitive problems with frailty progression and subsequent all-cause mortality risk: a large-scale cohort study.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2026
    Article
  2. Lifecourse socioeconomic status and subjective cognitive decline among diverse older adults.The journals of gerontology. Series B, Psychological sciences and social sciences · 2026
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  10. Subjective cognitive decline among diverse older adults: Prevalence and associations with objective cognition.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2025
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  18. fNIRS as a biomarker for individuals with subjective memory complaints and MCI.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2024
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Allan Gustavo BrigolaBacharel em Gerontologia, Mestrando no Programa de Pós-Graduação em Enfermagem da Universidade Federal de São Carlos.
Carlene Souza Silva ManziniEnfermeiro, Mestrando no Programa de Pós-Graduação em Enfermagem da Universidade Federal de São Carlos.
Gabriel Brassi Silveira OliveiraEnfermeiro, Mestrando no Programa de Pós-Graduação em Enfermagem da Universidade Federal de São Carlos.
Ana Carolina OttavianiBacharel em Gerontologia, Mestrando no Programa de Pós-Graduação em Enfermagem da Universidade Federal de São Carlos.
Michelli Pacheco SakoEnfermeiro, Mestrando no Programa de Pós-Graduação em Enfermagem da Universidade Federal de São Carlos.
Francisco Assis Carvalho ValeMédico Neurologista, Professor de Medicina e docente do Programa de Pós-Graduação em Enfermagem, da Universidade Federal de São Carlos.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The aging process can be accompanied by a slight decline in cognitive functioning, and subjective memory complaints (SMC) appear to be common in the elderly population.

objectiveTo determine whether SMC is associated with cognitive loss or depression and can predict dementia.

methodsA systematic review of the literature was conducted. Articles were selected on the following databases, LILACS, SCOPUS, SCiELO, PubMed and Web of Science from August to October 2013. Article selection was based on inclusion and exclusion criteria. Studies published between 2010 and 2013, written in English, Spanish or Portuguese, involving populations 65 years or older, were included. Reviews were excluded.

resultsAfter the selection, a summary of the 20 articles retrieved was carried out. Of the total articles retrieved, fifteen were cross-sectional studies and five were longitudinal studies. Most of the cross-sectional studies associated SMC with depression, objective cognitive impairment and anxiety. The emergence of dementia in people with SMC was evidenced in longitudinal studies. Albeit less frequently, SMC were also associated with reduced quality of life, impairment in Activities of Daily Living (ADL), emergence of neuropsychiatric symptoms, lower hippocampal volume, amygdala volume reduction, increased activation of the left temporal, bilateral thalamus, caudate and posterior cingulate, and with the occurrence of ApoE ε4.

conclusionSMC may be associated with changes in mood and/or cognition, and its occurrence appears to increase the likelihood of dementia. In order to further our understanding of the topic, future studies should consider the recruitment of representative samples with control groups and longitudinal designs.

Indexed as

agedanxietydementiadepressionmemory

Identifiers

PMID29213941
PMCPMC5618991

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.