ArticleDementia & neuropsychologia
Analysis of word number and content in discourse of patients with mild to moderate Alzheimer's disease.
Article in Dementia & neuropsychologia. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 1 of them a synthesis that pooled it.
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Who cites it
16 citing papers in PubMed, 1 synthesis or guideline pooled it, 42 citations in OpenAlex.
- A systematic literature review of automatic Alzheimer's disease detection from speech and language.Journal of the American Medical Informatics Association : JAMIA · 2020Pooled it
- Dependency Grammar Approach to the Syntactic Complexity in the Discourse of Alzheimer Patients.Behavioral sciences (Basel, Switzerland) · 2025Article
- Association of language markers with future cognitive impairment and presence of limbic predominant age related TDP-43 encephalopathy.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2025Article
- The Optimization of a Natural Language Processing Approach for the Automatic Detection of Alzheimer's Disease Using GPT Embeddings.Brain sciences · 2024Article
- The Optimization of a Natural Language Processing Approach for the Automatic Detection of Alzheimer's Disease Using GPT Embeddings.medRxiv : the preprint server for health sciences · 2024Article
- Automatic speech analysis for detecting cognitive decline of older adults.Frontiers in public health · 2024Article
- Further evaluation of narrative description as a measure of cognitive function in Alzheimer's disease.Neuropsychology · 2023Article
- Neuropsychological endpoints for clinical trials in methylmalonic acidemia and propionic acidemia: A pilot study.Molecular genetics and metabolism reports · 2023Article
- Speech error rates after a sports-related concussion.Frontiers in psychology · 2023Article
- Semantic Feature Extraction Using SBERT for Dementia Detection.Brain sciences · 2022Article
- Identification of digital voice biomarkers for cognitive health.Exploration of medicine · 2020Article
- Voice quality and speech fluency distinguish individuals with Mild Cognitive Impairment from Healthy Controls.PloS one · 2020Article
- Narrative impairment, white matter damage and CSF biomarkers in the Alzheimer's disease spectrum.Aging · 2019Article
- Connected speech and language in mild cognitive impairment and Alzheimer's disease: A review of picture description tasks.Journal of clinical and experimental neuropsychology · 2018Review
- Word retrieval in picture descriptions produced by individuals with Alzheimer's disease.Journal of clinical and experimental neuropsychology · 2016Article
- A tutorial on discourse analysis in healthy and pathological ageing.International journal of language & communication disordersArticle
Corrections and comments
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Authors and funding
4 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Alzheimer's disease (AD) is characterized by impairments in memory and other cognitive functions such as language, which can be affected in all aspects including discourse. A picture description task is considered an effective way of obtaining a discourse sample whose key feature is the ability to retrieve appropriate lexical items. There is no consensus on findings showing that performance in content processing of spoken discourse deteriorates from the mildest phase of AD.
objectiveTo compare the quantity and quality of discourse among patients with mild to moderate AD and controls.
methodsA cross-sectional study was designed. Subjects aged 50 years and older of both sexes, with one year or more of education, were divided into three groups: control (CG), mild AD (ADG1) and moderate AD (ADG2). Participants were asked to describe the "cookie theft" picture. The total number of complete words spoken and information units (IU) were included in the analysis.
resultsThere was no significant difference among groups in terms of age, schooling and sex. For number of words spoken, the CG performed significantly better than both the ADG 1 and ADG2, but no difference between the two latter groups was found. CG produced almost twice as many information units as the ADG1 and more than double that of the ADG2. Moreover, ADG2 patients had worse performance on IUs compared to the ADG1.
conclusionDecreased performance in quantity and content of discourse was evident in patients with AD from the mildest phase, but only content (IU) continued to worsen with disease progression.
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