ReviewDementia & neuropsychologia
Cognitive impairment in Wilson's disease.
Review in Dementia & neuropsychologia. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
14 citing papers in PubMed, 41 citations in OpenAlex.
- Phenotype-specific white matter microstructural alterations and their clinical correlates in Wilson disease.Scientific reports · 2026Article
- Neuropsychiatric manifestations of Wilson's disease.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2026Review
- Oxidative Stress and Psychiatric Symptoms in Wilson's Disease.International journal of molecular sciences · 2025Article
- Effect of high-frequency repetitive transcranial magnetic stimulation on cognitive impairment in WD patients based on inverse probability weighting of propensity scores.Frontiers in neuroscience · 2024Article
- Neurological Wilson's Disease Signs-Hepatic Encephalopathy or Copper Toxicosis?Diagnostics (Basel, Switzerland) · 2023Review
- Clinical significance of self-descriptive apathy assessment in patients with neurological form of Wilson's disease.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2022Article
- Role of metals in Alzheimer's disease.Metabolic brain disease · 2021Review
- Altered large-scale functional brain networks in neurological Wilson's disease.Brain imaging and behavior · 2020Article
- Eye movement abnormalities are associated with brainstem atrophy in Wilson disease.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2020Article
- Psychiatric manifestations in Wilson's disease: possibilities and difficulties for treatment.Therapeutic advances in psychopharmacology · 2018Review
- Article
- Evaluation of Non-Motor Symptoms in Wilson Disease Using the Parkinson's Disease Nonmotor Symptoms Questionnaire: A Pilot Cross-Sectional Study and Critical Assessment.Annals of Indian Academy of NeurologyArticle
- Bedside cognitive assessments in Wilson's disease: Comparing cases and matched controls.Journal of neurosciences in rural practiceArticle
- Which factors are associated with global cognitive impairment in Wilson's disease?Dementia & neuropsychologiaArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Wilson's disease (WD) or hepatolenticular degeneration is a rare, genetic and systemic disease, caused by a deficit in the metabolism of copper, leading to its accumulation in different organs, mainly the liver, followed by the central nervous system, especially the basal ganglia. When symptoms begin between the second and third decades of life, approximately 50% of the patients show neurological symptoms. Although dystonia and dysarthria are the most common neurological signs, cognitive changes have been reported since the first cases were described in 1912. Memory change is one of the most common impairments, but other cognitive changes have been reported, including dementia in untreated cases. In this article we review the cognitive changes in WD patients and the occurrence of dementia.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.