Evidence map›Paper›PMID 29213501›Full record

ArticleDementia & neuropsychologia

Type 2 diabetes mellitus in the pathophysiology of Alzheimer's disease.

Aparecida Marcelino de Nazareth

Open access · diamondAbstract read
In one paragraph

Article in Dementia & neuropsychologia. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed
3.1field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 58 citations in OpenAlex.

  1. Review
  2. Associations Between Diabetes Mellitus and Neurodegenerative Diseases.International journal of molecular sciences · 2025
    Review
  3. Efficacy and Mechanism ofNutrients · 2024
    Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Amyloid Beta in Aging and Alzheimer's Disease.International journal of molecular sciences · 2022
    Review
  11. Targeting NLRP3-Mediated Neuroinflammation in Alzheimer's Disease Treatment.International journal of molecular sciences · 2022
    Review
  12. Review
  13. Toxicological research · 2021
    Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Review
  19. Neuroinflammation in mouse models of Alzheimer's disease.Clinical & experimental neuroimmunology · 2018
    Review
  20. Precision Medicine for Alzheimer's Disease Prevention.Healthcare (Basel, Switzerland) · 2018
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author at 1 institution in 1 country.

Aparecida Marcelino de NazarethPhysiotherapist, Specialist in Neurofunctional Physical Therapy, Master of Neurosciences from the (UFSC), SC, Brazil, and PhD in Sciences (Pharmacology and Medicinal Chemistry) from the Federal University of Rio de Janeiro (UFRJ), RJ, Brazil.
Universidade Federal de Santa Catarina · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Both Alzheimer's disease (AD) and type 2 diabetes mellitus (DM) are two common forms of disease worldwide and many studies indicate that people with diabetes, especially DM, are at higher risk of developing AD. AD is characterized by progressive cognitive decline and accumulation of β-amyloid (Aβ) forming senile plaques. DM is a metabolic disorder characterized by hyperglycemia in the context of insulin resistance and relative lack of insulin. Both diseases also share common characteristics such as loss of cognitive function and inflammation. Inflammation resulting from Aβ further induces production of Aβ

Indexed as

Alzheimer's diseaseinflammationtype 2 diabetes mellitus

Identifiers

PMID29213501
PMCPMC5710678
OpenAlexW2988470961

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.