Evidence map›Paper›PMID 29213425›Full record

ArticleDementia & neuropsychologia

Phototest for neurocognitive screening in multiple sclerosis.

Joana Pinto, Emanuela Lopes, Gerly Gonçalves, Ângela Silva, Carnero-Pardo, Bruno Peixoto

Open access · diamondAbstract read
In one paragraph

Article in Dementia & neuropsychologia. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact, top 97% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 2 countries.

Joana PintoCESPU, Instituto de Investigação e Formação Avançada em Ciências e Tecnologias da Saúde, Gandra, Portugal.
Emanuela LopesCentro Hospitalar do Alto Ave, Guimarães, Portugal.
Gerly GonçalvesCentro Hospitalar do Alto Ave, Guimarães, Portugal.
Ângela SilvaCentro Hospitalar do Alto Ave, Guimarães, Portugal.
Carnero-PardoCognitive Behavioral Neurology Unit of the Hospital Universitario Virgen de las Nieves, Granada, Spain.
Bruno PeixotoCESPU, Instituto Superior de Ciências da Saúde - Norte (Sciences Department), Gandra, Portugal.
Centro Hospitalar de Trás os Montes e Alto Douro · PTHospital Universitario Virgen de las Nieves · ESInstituto de Investigação e Formação Avançada em Ciências e Tecnologias da Saúde

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Multiple Sclerosis (MS) is one of the most common neurological disorders. Cognitive dysfunction is considered a clinical marker of MS, where approximately half of patients with MS have cognitive impairment.

objectiveThe Phototest (PT) is a brief cognitive test with high diagnostic sensitivity, accuracy and cost-effectiveness for detecting cognitive deterioration. Our aim was to test the utility of the PT as a neurocognitive screening instrument for MS.

methodsThe study enrolled 30 patients with different types of MS from an outpatient clinic as well as 19 healthy participants. In conjunction with the PT, the Montreal Cognitive Assessment (MoCA), Barthel Index (BI), Expanded Disability Status Scale (EDSS), and Fatigue Severity Scale (FSS) were administered.

resultsThe MS group obtained significantly lower results on all domains of the PT, except for the naming task. The PT showed good concurrent validity with the MoCA. In direct comparison to the MoCA, PT showed a greater area under the curve and higher levels of sensitivity and specificity for MS neurocognitive impairments. A cut-off score of 31 on the Phototest was associated with sensitivity of 100% and specificity of 76.7%.

conclusionThe PT is a valid, specific, sensitive and brief test that is not dependent on motor functions. The instrument could be an option for neurocognitive screening in MS, especially in identifying cases for further neuropsychological assessment and intervention.

Indexed as

Expanded Disability Status ScaleFatigue Severity ScaleMontreal Cognitive Assessmentmultiple sclerosisPhototest

Identifiers

PMID29213425
PMCPMC5674908
OpenAlexW2335780117

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.