Evidence map›Paper›PMID 29213318›Full record

ArticleBiotechnology for biofuels2017

Targeted redox and energy cofactor metabolomics in

Kyle Sander, Keiji G Asano, Deepak Bhandari, Gary J Van Berkel, Steven D Brown, Brian Davison, Timothy J Tschaplinski

Abstract read
In one paragraph

Article in Biotechnology for biofuels, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Molecules (Basel, Switzerland) · 2026
    Article
  2. Article
  3. Advances and Applications ofFrontiers in microbiology · 2020
    Review
  4. Assessing Cofactor Usage inFrontiers in microbiology · 2019
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Kyle SanderDepartment of Chemical and Biomolecular Engineering, University of Tennessee, Knoxville, TN USA.
Keiji G AsanoChemical Sciences Division, Oak Ridge National Laboratory, Oak Ridge, TN USA.
Deepak BhandariChemical Sciences Division, Oak Ridge National Laboratory, Oak Ridge, TN USA.
Gary J Van BerkelChemical Sciences Division, Oak Ridge National Laboratory, Oak Ridge, TN USA.
Steven D BrownBredesen Center for Interdisciplinary Graduate Research and Education, University of Tennessee, Knoxville, TN USA.
Brian DavisonDepartment of Chemical and Biomolecular Engineering, University of Tennessee, Knoxville, TN USA.
Timothy J TschaplinskiBiosciences Division, Oak Ridge National Laboratory, Oak Ridge, TN USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

background

resultsThrough our validations, we verified the handling and storage stability of these metabolites, and verified extraction matrices and extraction solvent were not suppressing mass spectrometry signals. We recovered adenylate energy charge ratios (a main quality indicator) above 0.82 for all extractions. NADH/NAD+ values of 0.26 and 0.04 for an

conclusionsOur validated protocols demonstrate and validate the extraction and analysis of selected redox and energy-related metabolites from two candidate consolidated bioprocessing biocatalysts,

Indexed as

Adenylate energy chargeClostridium thermocellumRedoxTargeted metabolomicsThermoanaerobacterium saccharolyticum

Identifiers

PMID29213318
PMCPMC5707896

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.