Evidence map›Paper›PMID 29213226›Full record

ArticleFrontiers in neuroscience2017

Transcranial Direct Current Stimulation (tDCS): A Beginner's Guide for Design and Implementation.

Hayley Thair, Amy L Holloway, Roger Newport, Alastair D Smith

7 registry-linked trialsAbstract read
In one paragraph

Article in Frontiers in neuroscience, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 7 registered trials, which are not on this map. Cited by 252 papers, 14 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
252citing papers in PubMed, 14 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04010149 naunknown statusnot on this mapstarted 2019, after this paper: background citation

The Impact of Concurrent Brain Stimulation and Working Memory Training on Cognitive Performance in Acquired Brain Injury

TypeinterventionalSponsorUniversity of BirminghamRan2019 to 2021Enrolled40ConditionsAcquired Brain InjuryArmsActive tDCS, SHAM tDCS
NCT04260815 nacompletednot on this mapstarted 2018, after this paper: background citation

The Effect of Transcranial Direct-current Stimulation on Discourse Production in Healthy Older Adults

TypeinterventionalSponsorKing's College LondonRan2018 to 2019Enrolled14ConditionsLanguage Disorders, Aphasia, StrokeArmsTranscranial direct-current stimulation (tDCS)
NCT04780152 phase2 / phase3unknown statusnot on this mapstarted 2021, after this paper: background citation

Assessment of Efficacy and Safety of Anodal Transcranial Direct Current Stimulation (TDCS) in Pediatric and Teenage Patients With Major Depressive Disorder During COVID-19 Pandemics

TypeinterventionalSponsorEl Instituto Nacional de Neurologia y Neurocirugia Manuel Velasco SuarezRan2021 to 2022Enrolled172ConditionsMajor Depressive DisorderArmsTranscranial Direct Current Stimulation, Placebo-simulation of transcranial direct current stimulation, Fluoxetine Tablets
NCT06349369 naunknown statusnot on this mapstarted 2024, after this paper: background citation

Effect of Transcranial Direct Current Stimulation (tDCS) on Inflammatory Biomarkers in Chronic Schizophrenia: A Randomised Double-Blind Controlled Trial.

TypeinterventionalSponsorAll India Institute of Medical Sciences, BhubaneswarRan2024 to 2026Enrolled60ConditionsChronic SchizophreniaArmstranscranial direct current stimulation
NCT06544122 nacompletednot on this mapstarted 2023, after this paper: background citation

Effect of Transcranial Direct Current Stimulation on the Voice

TypeinterventionalSponsorUniversidade Federal de PernambucoRan2023 to 2024Enrolled16ConditionsVoice and Resonance Disorders, Transcranial Direct Current Stimulation, Voice DisturbanceArmsTranscranial direct current stimulation
NCT06729437 narecruitingnot on this mapstarted 2024, after this paper: background citation

Effectiveness of Transcranial Direct Current Stimulation on Functionality and Pain in Individuals With Patellar Tendinopathy: Randomized Clinical Trial

TypeinterventionalSponsorUniversity of ValenciaRan2024 to 2027Enrolled42ConditionsPatellar TendinopathyArmstDCS + Therapeutic eccentric exercise, Sham tDCS + Therapeutic eccentric exercise
NCT07217223 narecruitingnot on this mapstarted 2025, after this paper: background citation

Spaced Transcranial Direct Current Stimulation for Treatment-Resistant Depression: A Home-Based Feasibility and Safety Study

TypeinterventionalSponsorUniversity of California, San DiegoRan2025 to 2027Enrolled10ConditionsTreatment Resistant Depression (TRD), Major Depressive Disorder (MDD)ArmsSpaced Transcranial Direct Current Stimulation (tDCS)
3 · Its place in the literature

Who cites it

252 citing papers in PubMed, 14 syntheses or guidelines pooled it.

  1. Pooled it
  2. Neuromodulation of the central nervous system for facial pain.Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics · 2026
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  15. Trial
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  20. Transcranial direct current stimulation is safe and feasible in hyperacute ischemic stroke (DICAST-SF trial).Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics · 2026
    Trial

192 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Hayley ThairSchool of Psychology, University of Nottingham, Nottingham, United Kingdom.
Amy L HollowaySchool of Psychology, University of Nottingham, Nottingham, United Kingdom.
Roger NewportSchool of Psychology, University of Nottingham, Nottingham, United Kingdom.
Alastair D SmithSchool of Psychology, University of Nottingham, Nottingham, United Kingdom.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Transcranial direct current stimulation (tDCS) is a popular brain stimulation method that is used to modulate cortical excitability, producing facilitatory or inhibitory effects upon a variety of behaviors. There is, however, a current lack of consensus between studies, with many results suggesting that polarity-specific effects are difficult to obtain. This article explores some of these differences and highlights the experimental parameters that may underlie their occurrence. We provide a general, practical snapshot of tDCS methodology, including what it is used for, how to use it, and considerations for designing an effective and safe experiment. Our aim is to equip researchers who are new to tDCS with the essential knowledge so that they can make informed and well-rounded decisions when designing and running successful experiments. By summarizing the varied approaches, stimulation parameters, and outcomes, this article should help inform future tDCS research in a variety of fields.

Indexed as

anodalbrain stimulationcathodalcortical modulationprotocoltranscranial direct current stimulation

Identifiers

PMID29213226
PMCPMC5702643

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

and 1 more above

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.