ReviewClinical reviews in bone and mineral metabolism2017
A Review on Bone Mineral Density Loss in Total Knee Replacements Leading to Increased Fracture Risk.
Review in Clinical reviews in bone and mineral metabolism, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04040764 (The Tritanium Uncemented Prosthesis Versus the Cemented Triathlon Prosthesis), which is not on this map. Cited by 17 papers, 3 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
The Tritanium Uncemented Prosthesis Versus the Cemented Triathlon Prosthesis
Who cites it
17 citing papers in PubMed, 3 syntheses or guidelines pooled it.
- Bone Mineral Density, Bone Biomarkers, and Joints in Acute, Post, and Long COVID-19: A Systematic Review.Viruses · 2024Pooled it
- Factors influencing periprosthetic bone mineral density in total knee arthroplasty: a systematic review.Archives of orthopaedic and trauma surgery · 2024Pooled it
- Prevalence and treatment rate of osteoporosis in patients undergoing total knee and hip arthroplasty: a systematic review and meta-analysis.Archives of osteoporosis · 2022Pooled it
- The relationship between stress shielding, bone density changes and implant migration, failure and fracture after total knee arthroplasty: A systematic review.Journal of experimental orthopaedics · 2025Review
- Osteoporosis is not associated with increased reoperation or fracture risk three years after total ankle arthroplasty: a retrospective cohort study.Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2025Article
- Management of Femoral Condyle Insufficiency Fractures Following Total Knee Arthroplasty (FCIF-TKA).Cureus · 2024Article
- Prevalence of Common Metabolic Bone Diseases Diagnosed by Dual-Energy X-Ray Absorptiometry Scanning and Blood Test in Outpatients With Osteoarthritis the Knee.Geriatric orthopaedic surgery & rehabilitation · 2024Article
- Radiographic Evaluation and Changes in Bone Density of the Humeral Side after Reverse Total Shoulder Arthroplasty.Journal of clinical medicine · 2023Article
- Bone Health Management in Elective Orthopaedic Surgery: A Claims-Based Observational Study.Geriatric orthopaedic surgery & rehabilitation · 2023Article
- Prevalence of osteoporosis and osteopenia in elderly patients scheduled for total knee arthroplasty.Archives of orthopaedic and trauma surgery · 2022Article
- Post-acute COVID syndrome (long COVID): What should radiographers know and the potential impact for imaging services.Radiography (London, England : 1995) · 2022Review
- Osteoporosis in Indian Patients Undergoing Elective Arthroplasty and Spinal Procedures: An Observational Study.Cureus · 2022Article
- Incidence of postoperative complications and non- periprosthetic fractures after total hip arthroplasty: A more than 10-year follow-up retrospective cohort study.Physical therapy research · 2021Article
- Prevalence and Risk Factors of Osteoporosis in Chinese Postmenopausal Women Awaiting Total Knee Arthroplasty.Clinical interventions in aging · 2021Article
- Risk for hip fracture before and after total knee replacement in Sweden.Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2020Article
- DXA evaluation of femoral bone mineral density and cortical width in patients with prior total knee arthroplasty.Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2019Article
- Polyethylene particles inserted over calvarium induce cancellous bone loss in femur in female mice.Bone reports · 2018Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The link between low bone mineral density (BMD) scores leading to greater fracture risk is well established in the literature; what is not fully understood is the impact of total knee replacements/revisions or arthroplasties on BMD levels. This literature review attempts to answer this question. Several different databases using specific key terms were searched, with additional papers retrieved via bibliographic review. Based on the available evidence, total knee replacements/revisions and arthroplasties lower BMD and thus increase fracture risk. This review also addresses the possible implications of this research and possible options to reduce this risk.
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Identifiers
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.