Evidence map›Paper›PMID 29213079›Full record

ArticleNature communications2017

Human CD26

Stefanie R Bailey, Michelle H Nelson, Kinga Majchrzak, Jacob S Bowers, Megan M Wyatt, Aubrey S Smith, Lillian R Neal, Keisuke Shirai, Carmine Carpenito, Carl H June and 2 more

Open access · goldAbstract read
In one paragraph

Article in Nature communications, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 76 papers.

0numbers the graph read from it
0cells of the map it votes in
76citing papers in PubMed
3.1field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

76 citing papers in PubMed, 103 citations in OpenAlex.

  1. Article
  2. C-terminal CD28 phosphorylation, pY218, modulates IL-2 secretion and therapeutic effect of CAR-T cells.Molecular therapy : the journal of the American Society of Gene Therapy · 2026
    Article
  3. Review
  4. Pharmacologic DPP-4 inhibition promotes CD8bioRxiv : the preprint server for biology · 2026
    Article
  5. Article
  6. Article
  7. Review
  8. Article
  9. Engineering resilient CAR T cells for immunosuppressive environment.Molecular therapy : the journal of the American Society of Gene Therapy · 2025
    Review
  10. Review
  11. Review
  12. Article
  13. Article
  14. Review
  15. Review
  16. Article
  17. Review
  18. Review
  19. Article
  20. Article

16 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 5 institutions in 3 countries.

Stefanie R BaileyDepartment of Microbiology and Immunology, Medical University of South Carolina, Charleston, SC, 29425, USA. flemins@musc.edu.
Michelle H NelsonDepartment of Microbiology and Immunology, Medical University of South Carolina, Charleston, SC, 29425, USA.ORCID http://orcid.org/0000-0001-7597-0923
Kinga MajchrzakDepartment of Microbiology and Immunology, Medical University of South Carolina, Charleston, SC, 29425, USA.
Jacob S BowersDepartment of Microbiology and Immunology, Medical University of South Carolina, Charleston, SC, 29425, USA.
Megan M WyattDepartment of Microbiology and Immunology, Medical University of South Carolina, Charleston, SC, 29425, USA.ORCID http://orcid.org/0000-0003-1316-260X
Aubrey S SmithDepartment of Microbiology and Immunology, Medical University of South Carolina, Charleston, SC, 29425, USA.
Lillian R NealDepartment of Microbiology and Immunology, Medical University of South Carolina, Charleston, SC, 29425, USA.
Keisuke ShiraiHematology/Oncology Division, Hollings Cancer Center, Medical University of South Carolina, Charleston, SC, 29425, USA.
Carmine CarpenitoDepartment of Pathology and Laboratory Medicine, University of Pennsylvania Cancer Center, Philadelphia, PA, 19104, USA.
Carl H JuneDepartment of Pathology and Laboratory Medicine, University of Pennsylvania Cancer Center, Philadelphia, PA, 19104, USA.ORCID http://orcid.org/0000-0003-0241-3557
Michael J ZillioxDepartment of Public Health Sciences, Stritch School of Medicine, Loyola University Chicago, Maywood, IL, 60153, USA.
Chrystal M PaulosDepartment of Microbiology and Immunology, Medical University of South Carolina, Charleston, SC, 29425, USA. paulos@musc.edu.
Medical University of South Carolina · USDartmouth College · USEli Lilly (United States) · USLoyola University Chicago · USUniversity of Pennsylvania · US

Funding

TCR TRANSDUCED CDB T CELLS FOR ADOPTIVE IMMUNOTHERAPYP01CA154778 · NCI · LOYOLA UNIVERSITY CHICAGO · PI NISHIMURA, MICHAEL I. · 2011 to 2015
$15.4M
Mechanisms of durable antitumor immunity via CD26hiCD4+ T cellsR01CA208514 · NCI · MEDICAL UNIVERSITY OF SOUTH CAROLINA · PI PAULOS, CHRYSTAL MARY · 2016 to 2020
$1.7M
Costimulatory mechanisms of antitumor Th17 cell immunityR01CA175061 · NCI · MEDICAL UNIVERSITY OF SOUTH CAROLINA · PI PAULOS, CHRYSTAL MARY · 2013 to 2017
$1.5M
Defining and translating the properties that sustain the antitumor efficacy of Th17 cellsF30CA200272 · NCI · MEDICAL UNIVERSITY OF SOUTH CAROLINA · PI BOWERS, JACOB S · 2015 to 2018
$182k
Elucidating the role of CD26 in T cell-mediated tumor immunityF31CA192787 · NCI · MEDICAL UNIVERSITY OF SOUTH CAROLINA · PI BAILEY, STEFANIE · 2015 to 2017
$131k
NCI NIH HHS F30 CA200272NCI NIH HHS F31 CA192787NCI NIH HHS P01 CA154778NCI NIH HHS R01 CA175061NCI NIH HHS R01 CA208514
6 · The paper itself

Abstract

CD8

Indexed as

Adoptive TransferAnimalsApoptosisbeta CateninCD4-Positive T-LymphocytesCD8-Positive T-LymphocytesCell MovementCytokinesDipeptidyl Peptidase 4Disease Models, AnimalGranzymesHumansImmunityImmunologic MemoryImmunotherapyLymphoid Enhancer-Binding Factor 1BCL2 protein, humanbeta CateninCytokinesDipeptidyl Peptidase 4DPP4 protein, humanGranzymesGZMB protein, humanLEF1 protein, humanLymphoid Enhancer-Binding Factor 1Lysosomal-Associated Membrane Protein 1Proto-Oncogene Proteins c-bcl-2Proto-Oncogene Proteins c-kit

Identifiers

PMID29213079
PMCPMC5719008
OpenAlexW2771398071

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.