Evidence map›Paper›PMID 29212661›Full record

ArticleGenes & development2017

Disruption of an RNA-binding hinge region abolishes LHP1-mediated epigenetic repression.

Scott Berry, Stefanie Rosa, Martin Howard, Marc Bühler, Caroline Dean

Open access · diamondAbstract read
In one paragraph

Article in Genes & development, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 42 citations in OpenAlex.

  1. Review
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  3. Adaptation of seed dormancy to maternal climate occurs via intergenerational transport of abscisic acid.Proceedings of the National Academy of Sciences of the United States of America · 2025
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  15. Evolutionarily ancient BAH-PHD protein mediates Polycomb silencing.Proceedings of the National Academy of Sciences of the United States of America · 2020
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 3 countries.

Scott BerryJohn Innes Centre, Norwich NR4 7UH, United Kingdom.ORCID 0000-0002-1838-4976
Stefanie RosaInstitute of Biochemistry and Biology, University of Potsdam, DE-14476 Potsdam-Golm, Germany.
Martin HowardJohn Innes Centre, Norwich NR4 7UH, United Kingdom.
Marc BühlerFriedrich Miescher Institute for Biomedical Research, 4058 Basel, Switzerland.
Caroline DeanJohn Innes Centre, Norwich NR4 7UH, United Kingdom.
John Innes Centre · GBFriedrich Miescher Institute · CHUniversity of Potsdam · DE

Funding

Biotechnology and Biological Sciences Research Council BB/J004588/1Biotechnology and Biological Sciences Research Council BBS/E/J/000PR9773
6 · The paper itself

Abstract

Epigenetic maintenance of gene repression is essential for development. Polycomb complexes are central to this memory, but many aspects of the underlying mechanism remain unclear. LIKE HETEROCHROMATIN PROTEIN 1 (LHP1) binds Polycomb-deposited H3K27me3 and is required for repression of many Polycomb target genes in

Indexed as

ArabidopsisArabidopsis ProteinsChromosomal Proteins, Non-HistoneEpigenetic RepressionGene Expression Regulation, PlantHistonesMutationPolycomb-Group ProteinsRNA-Binding MotifsArabidopsis ProteinsChromosomal Proteins, Non-HistoneHistoneslike heterochromatin protein 1Polycomb-Group Proteinschromatinepigeneticsplant biologyPolycombRNA

Identifiers

PMID29212661
PMCPMC5749160
OpenAlexW2774096656

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.