ArticleJMIR mHealth and uHealth2017
Mobile Health Intervention to Increase Oral Cancer Therapy Adherence in Patients With Chronic Myeloid Leukemia (The REMIND System): Clinical Feasibility and Acceptability Assessment.
Article in JMIR mHealth and uHealth, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers, 4 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
21 citing papers in PubMed, 4 syntheses or guidelines pooled it, 41 citations in OpenAlex.
- Feasibility and preliminary effects of mhealth supportive care interventions in adults with myeloid neoplasms: a systematic review.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2026Pooled it
- The Efficacy of Digital Interventions on Adherence to Oral Systemic Anticancer Therapy Among Patients With Cancer: Systematic Review and Meta-Analysis.JMIR cancer · 2025Pooled it
- Experiences of Patients With Cancer Using Electronic Symptom Management Systems: Qualitative Systematic Review and Meta-Synthesis.Journal of medical Internet research · 2024Pooled it
- Smartphone Apps for Patients With Hematologic Malignancies: Systematic Review and Evaluation of Content.JMIR mHealth and uHealth · 2022Pooled it
- The trials and tribulations of conducting an m-health pilot randomized controlled trial to improve oral cancer therapy adherence: recommendations for future multisite, non-drug clinical trials.BMC research notes · 2019Trial
- Mobile Health App Attitudes and Adoption Among Oncology Providers: Cross-Sectional National Survey.Journal of medical Internet research · 2026Article
- Perspectives of Frontline Clinicians and End-Line Users on Smartphone-Based Photography for Assessing Traumatic Dental Injuries: Focus Group Interview Study and Thematic Analysis.JMIR human factors · 2026Article
- A smart pill bottle and text messaging intervention for promoting medication adherence in patients with chronic myeloid leukemia: a pilot study of txt4 TKI.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2025Article
- Co-Design, Development, and Evaluation of a Mobile Solution to Improve Medication Adherence in Cancer: Design Science Research Approach.JMIR cancer · 2024Article
- Implementing Telemedicine in Clinical Practice in the First Digital Hematology Unit: Feasibility Study.JMIR formative research · 2023Article
- An investigation of the use of app technology to support clinical management of patients with chronic myeloid leukaemia (CML).Journal of oncology pharmacy practice : official publication of the International Society of Oncology Pharmacy Practitioners · 2023Article
- Article
- mHealth for Medication and Side Effect Monitoring: Patients' Attitudes Toward Smart Devices for Managing Oral Chemotherapy During Lung Cancer Treatment.International Conference on Pervasive Computing Technologies for Healthcare : [proceedings]. International Conference on Pervasive Computing Technologies for Healthcare · 2023Article
- Women with breast cancer's perceptions of nurse-led telephone-based motivational interviewing consultations to enhance adherence to adjuvant endocrine therapy: a qualitative study.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2022Article
- Investigation of Intervention Solutions to Enhance Adherence to Oral Anticancer Medicines in Adults: Overview of Reviews.JMIR cancer · 2022Review
- Person-Generated Health Data in Women's Health: Protocol for a Scoping Review.JMIR research protocols · 2021Article
- Interventions to Enhance Adherence to Oral Antineoplastic Agents: A Scoping Review.Journal of the National Cancer Institute · 2020Article
- Maximizing the effectiveness of oral therapies in lymphoid cancers: research gaps and unmet needs.Leukemia & lymphoma · 2019Review
- Mobile-Based Oral Chemotherapy Adherence-Enhancing Interventions: Scoping Review.JMIR mHealth and uHealth · 2018Article
- Challenges to the design and testing supportive interventions for cancer patients treated with oral oncolytic agents.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2018Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
14 authors at 9 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundOptimal dosing of oral tyrosine kinase inhibitor therapy is critical to treatment success and survival of patients with chronic myeloid leukemia (CML). Drug intolerance secondary to toxicities and nonadherence are significant factors in treatment failure.
objectiveThe objective of this study was to develop and pilot-test the clinical feasibility and acceptability of a mobile health system (REMIND) to increase oral drug adherence and patient symptom self-management among people with CML (chronic phase).
methodsA multifaceted intervention was iteratively developed using the intervention development framework by Schofield and Chambers, consisting of defining the patient problem and iteratively refining the intervention. The clinical feasibility and acceptability were examined via patient and intervention nurse interviews, which were audiotaped, transcribed, and deductively content analyzed.
resultsThe intervention comprised 2 synergistically operating elements: (1) daily medication reminders and routine assessment of side effects with evidence-based self-care advice delivered in real time and (2) question prompt list (QPL) questions and routinely collected individual patient adherence and side effect profile data used to shape nurses' consultations, which employed motivational interviewing to support adoption of self-management behaviors. A total of 4 consultations and daily alerts and advice were delivered over 10 weeks. In total, 58% (10/17) of patients and 2 nurses participated in the pilot study. Patients reported several benefits of the intervention: help in establishing medication routines, resolution of symptom uncertainty, increased awareness of self-care, and informed decision making. Nurses also endorsed the intervention: it assisted in establishing pill-taking routines and patients developing effective solutions to adherence challenges.
conclusionsThe REMIND system with nurse support was usable and acceptable to both patients and nurses. It has the potential to improve adherence and side-effect management and should be further evaluated.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.