ArticleBMC ophthalmology2017
A pilot investigation of audiovisual processing and multisensory integration in patients with inherited retinal dystrophies.
Article in BMC ophthalmology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.
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Who cites it
9 citing papers in PubMed, 12 citations in OpenAlex.
- Article
- A Pilot Investigation of Visual Pathways in Patients with Mild Traumatic Brain Injury.Neurology international · 2023Article
- Auditory and olfactory findings in patients with USH2A-related retinal degeneration-Findings at baseline from the rate of progression in USH2A-related retinal degeneration natural history study (RUSH2A).American journal of medical genetics. Part A · 2021Article
- Vestibular Stimulation May Drive Multisensory Processing: Principles for Targeted Sensorimotor Therapy (TSMT).Brain sciences · 2021Article
- Partial recovery of visual function in a blind patient after optogenetic therapy.Nature medicine · 2021Article
- BBSome Component BBS5 Is Required for Cone Photoreceptor Protein Trafficking and Outer Segment Maintenance.Investigative ophthalmology & visual science · 2020Article
- Frontal cortex selectively overrides auditory processing to bias perception for looming sonic motion.Brain research · 2020Article
- Acoustic noise and vision differentially warp the auditory categorization of speech.The Journal of the Acoustical Society of America · 2019Article
- Psychobiological Responses Reveal Audiovisual Noise Differentially Challenges Speech Recognition.Ear and hearingArticle
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Authors and funding
3 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundIn this study, we examined audiovisual (AV) processing in normal and visually impaired individuals who exhibit partial loss of vision due to inherited retinal dystrophies (IRDs).
methodsTwo groups were analyzed for this pilot study: Group 1 was composed of IRD participants: two with autosomal dominant retinitis pigmentosa (RP), two with autosomal recessive cone-rod dystrophy (CORD), and two with the related complex disorder, Bardet-Biedl syndrome (BBS); Group 2 was composed of 15 non-IRD participants (controls). Audiovisual looming and receding stimuli (conveying perceptual motion) were used to assess the cortical processing and integration of unimodal (A or V) and multimodal (AV) sensory cues. Electroencephalography (EEG) was used to simultaneously resolve the temporal and spatial characteristics of AV processing and assess differences in neural responses between groups. Measurement of AV integration was accomplished via quantification of the EEG's spectral power and event-related brain potentials (ERPs).
resultsResults show that IRD individuals exhibit reduced AV integration for concurrent audio and visual (AV) stimuli but increased brain activity during the unimodal A (but not V) presentation. This was corroborated in behavioral responses, where IRD patients showed slower and less accurate judgments of AV and V stimuli but more accurate responses in the A-alone condition.
conclusionsCollectively, our findings imply a neural compensation from auditory sensory brain areas due to visual deprivation.
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