Evidence map›Paper›PMID 29212496›Full record

ArticleRespiratory research2017

Pulmonary function, exhaled nitric oxide and symptoms in asthma patients with obesity: a cross-sectional study.

Marise J Kasteleyn, Tobias N Bonten, Renée de Mutsert, Willemien Thijs, Pieter S Hiemstra, Saskia le Cessie, Frits R Rosendaal, Niels H Chavannes, Christian Taube

Abstract read
In one paragraph

Article in Respiratory research, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Mitochondrial Dysfunction and Metabolic Reprogramming in Obesity and Asthma.International journal of molecular sciences · 2024
    Review
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  10. Review
  11. Article
  12. Article
  13. Article
  14. Review
  15. Article
  16. Article
  17. Article
  18. Article
  19. Article
  20. Bioenergetic Differences in the Airway Epithelium of LeanAntioxidants & redox signaling · 2019
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Marise J KasteleynDepartment of Pulmonology, Leiden University Medical Center, V6-22, PO Box 9600, 2300 RC, Leiden, the Netherlands.
Tobias N BontenDepartment of Pulmonology, Leiden University Medical Center, V6-22, PO Box 9600, 2300 RC, Leiden, the Netherlands. t.n.bonten@lumc.nl.
Renée de MutsertDepartment of Clinical Epidemiology, Leiden University Medical Center, Leiden, the Netherlands.
Willemien ThijsDepartment of Pulmonology, Leiden University Medical Center, V6-22, PO Box 9600, 2300 RC, Leiden, the Netherlands.
Pieter S HiemstraDepartment of Pulmonology, Leiden University Medical Center, V6-22, PO Box 9600, 2300 RC, Leiden, the Netherlands.
Saskia le CessieDepartment of Clinical Epidemiology, Leiden University Medical Center, Leiden, the Netherlands.
Frits R RosendaalDepartment of Clinical Epidemiology, Leiden University Medical Center, Leiden, the Netherlands.
Niels H ChavannesDepartment of Public Health and Primary Care, Leiden University Medical Center, Leiden, the Netherlands.
Christian TaubeDepartment of Pulmonology, Leiden University Medical Center, V6-22, PO Box 9600, 2300 RC, Leiden, the Netherlands.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundObesity is a risk factor for the development of asthma. In patients with obesity the diagnosis of asthma is often based on symptoms, but without objective measurements. Nevertheless, obesity-associated asthma is recognized as a distinct asthma phenotype. Therefore, this study explores lung function and symptoms in asthma patients with and without obesity.

methodsThe Netherlands Epidemiology of Obesity (NEO) study is a population-based cohort study with 6671 participants (aged 45-65 years) of whom 472 had asthma. Of this latter group, linear regression analysis was used to examine differences in lung function and symptoms between asthma patients with (n = 248) and without obesity (n = 224), and between asthma patients with and without increased Fe

resultsAsthma patients with obesity had lower predicted FEV

conclusionAsthma patients with obesity had lower FEV

Indexed as

AgedAsthmaCohort StudiesCross-Sectional StudiesFemaleForced Expiratory VolumeHumansLungMaleMiddle AgedNetherlandsNitric OxideObesityProspective StudiesRespiratory Function TestsNitric OxideAsthmaFeNOLung functionObesitySymptoms

Identifiers

PMID29212496
PMCPMC5719519

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.