Evidence map›Paper›PMID 29212443›Full record

ArticleBMC infectious diseases2017

The current incidence, prevalence, and residual risk of hepatitis B viral infections among voluntary blood donors in China.

Ling Li, Tingting Han, Liang Zang, Libin Niu, Weifang Cheng, Hongkeng Lin, Ka Yi Li, Ruan Cao, Binghai Zhao, Yuqiang Liu and 5 more

Open access · goldAbstract read
In one paragraph

Article in BMC infectious diseases, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
3.5field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 51 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 9 institutions in 2 countries.

Ling LiInstitute of Blood Transfusion, Chinese Academy of Medical Sciences and Peking Union Medical College, Chengdu, Sichuan, China.
Tingting HanNo. 1 People's Hospital of Anqing, Anqing, Anhui, China.
Liang ZangDalian Blood Center, Dalian, Liaoning, China.
Libin NiuChangzhi Blood Center, Changzhi, Shanxi, China.
Weifang ChengAnhui Blood Center, Hefei, Anhui, China.
Hongkeng LinFujian Blood Center, Fuzhou, Fujian, China.
Ka Yi LiCooper Medical School of Rowan University, Camden, USA.
Ruan CaoMianyang Blood Center, Mianyang, Sichuan, China.
Binghai ZhaoNanchong Blood Center, Nanchong, Sichuan, China.
Yuqiang LiuKaifeng Blood Center, Kaifeng, Henan, China.
Guojin OuInstitute of Blood Transfusion, Chinese Academy of Medical Sciences and Peking Union Medical College, Chengdu, Sichuan, China.
Xiao LiuNo. 1 People's Hospital of Deyang, Deyang, Sichuan, China.
Yingjie QiAnhui Provincial Infection Hospital, Hefei, Anhui, China.
Yanhua LiDepartment of Pathology, New York University School of Medicine, NYU Langone Health, New York, USA.
Zhong LiuInstitute of Blood Transfusion, Chinese Academy of Medical Sciences and Peking Union Medical College, Chengdu, Sichuan, China. liuz@ibt.pumc.edu.cn.
Chinese Academy of Medical Sciences & Peking Union Medical College · CNAnhui Provincial Hospital · CNAnqing City Hospital · CNChangzhi University · CNCooper Medical School of Rowan University · USDeyang Stomatological Hospital · CNFujian Blood Center · CNNew York University · USSichuan Mianyang 404 Hospital · CN

Funding

This study was funded by the CAMS Initiative for Innovative Medicine 2016-I2M-3-024This study was funded by the PUMC Youth Fund 3332015121
6 · The paper itself

Abstract

backgroundThere are few data available on the prevalence, incidence, and residual risk of transfusion-transmitted HBV (TT-HBV) infections among Chinese blood donors. This study investigated the demographic characteristics of blood donors, as well as the prevalence, incidence, and residual risk (RR) of TT-HBV infections in six large blood centers in different regions of China.

methodsThe demographic characteristics and HBV screening test results of blood donors from six blood centers in different regions in China were collected and analyzed. The hepatitis B surface antigen (HBsAg) yield approach was used to estimate the incidence of HBV. Then, the RR of TT-HBV infections was evaluated using the incidence-window period model.

resultsThe majority of donors were between 18 and 35 years old (including 35), with the exception of the Changzhi Blood Center where a majority of donors were between 35 and 55 years old (including 55). The prevalences of HBV were 0.13%, 0.078%, 0.16%, 0.07%, 0.20%, 0.25% in Hefei, Dalian, Changzhi, Kaifeng, Mianyang and Fujian, respectively. The estimated corresponding incidences were 213.44, 161.59, 989.80, 278.05, 125.31 and 352.19 per 10

conclusionDespite the introduction of more sensitive assays in blood screening, our data revealed that the current residual risk of TT-HBV infection was still high (overall 56.53 per 10

Indexed as

AdolescentAdultAge FactorsBlood DonorsBlood TransfusionChinaFemaleHepatitis BHepatitis B Surface AntigensHepatitis B virusHumansIncidenceMaleMiddle AgedPrevalenceRiskHepatitis B Surface AntigensDonorsHBVResidual riskTransfusion

Identifiers

PMID29212443
PMCPMC5719753
OpenAlexW2771946819

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.