ArticleDiabetes & vascular disease research2018
Impact of metabolic control on macular thickness in diabetic macular oedema.
Article in Diabetes & vascular disease research, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.
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Who cites it
8 citing papers in PubMed, 18 citations in OpenAlex.
- One-year results of visual response following intravitreal novel anti-VEGF injection for diabetic macular edema in a Latino population.International journal of retina and vitreous · 2025Article
- A Cross-Sectional Study of Various Imaging and Biochemical Biomarkers in Patients with Diabetic Macular Edema in Different Stages of Diabetic Retinopathy.Clinical ophthalmology (Auckland, N.Z.) · 2022Article
- Influence of glycaemic control on macular thickness in diabetic retinopathy.Endocrinology, diabetes & metabolism · 2022Article
- Efficacy of topical dorzolamide 2% in diabetic cystoid macular edema.International journal of ophthalmology · 2021Article
- Systemic risk factors contribute differently to the development of proliferative diabetic retinopathy and clinically significant macular oedema.Diabetologia · 2020Article
- Genotypes and Phenotypes: A Search for Influential Genes in Diabetic Retinopathy.International journal of molecular sciences · 2020Review
- Article
- Ocular complications of diabetes mellitus in a pediatric population and proposals for screening and follow-up programs.Therapeutic advances in ophthalmologyArticle
Corrections and comments
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Authors and funding
2 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeTo investigate the impact of metabolic control on macular thickness measured using optical coherence tomography in patients with diabetic retinopathy with or without macular oedema.
methodsA total of 124 patients with diabetic retinopathy ( n = 70 without macular oedema and n = 54 with macular oedema) were enrolled. Optical coherence tomography parameters measured included central macular thickness and total macular volume. Metabolic factors with correlation to optical coherence tomography parameters were fasting plasma glucose, glycosylated haemoglobin, triglyceride, low-density lipoprotein and estimated glomerular filtration rate. Multiple linear regression models were used to evaluate associations between optical coherence tomography parameters and metabolic factors.
resultsHigher glycosylated haemoglobin values were correlated with increased central macular thickness in patients without macular oedema ( R = 0.289, p = 0.015), whereas glycosylated haemoglobin values were inversely associated with central macular thickness in patients with macular oedema ( R = -0.374, p = 0.005). Both were found to be statistically significant after adjusting for age, sex and diabetic retinopathy severity in addition to other metabolic factors ( p = 0.009 and p = 0.002, respectively).
conclusionStrict metabolic control may not be associated with better macular thickness in diabetic patients with co-existing macular oedema.
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