Evidence map›Paper›PMID 29212313›Full record

ArticleGut and liver2018

Clinical Outcomes of Standard Triple Therapy Plus Probiotics or Concomitant Therapy for

Jae Hyun Jung, In Kuk Cho, Chang Hee Lee, Gwan Gyu Song, Ji Hyun Lim

Abstract read
In one paragraph

Article in Gut and liver, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Review
  2. Article
  3. Microorganisms · 2024
    Review
  4. Study of the Effect of Baicalin fromInternational journal of molecular sciences · 2023
    Article
  5. The Eradication ofPathogens (Basel, Switzerland) · 2023
    Article
  6. Review
  7. Current and Future Treatment of Helicobacter pylori Infections.Advances in experimental medicine and biology · 2019
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Jae Hyun JungKorea University College of Medicine, Seoul, Korea.
In Kuk ChoDivision of Gastroenterology, Department of Internal Medicine, Incheon Sarang Hospital, Incheon, Korea.
Chang Hee LeeDivision of Gastroenterology, Department of Internal Medicine, Incheon Sarang Hospital, Incheon, Korea.
Gwan Gyu SongKorea University College of Medicine, Seoul, Korea.
Ji Hyun LimDivision of Gastroenterology, Department of Internal Medicine, Incheon Sarang Hospital, Incheon, Korea.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

BACKGROUND/

aimsThe efficacy of standard triple therapy (STT) in treating

methodsWe reviewed the medical records of 361 patients who received either STP (n=286) or CT (n=75). The STP group received STT combined with a probiotic preparation for 1 week. The CT group received STT and metronidazole for 1 week.

resultsThe intention-to-treat and per-protocol eradication rates were 83.6% (95% confidence interval [CI], 79.0 to 87.7) and 87.1% (95% CI, 81.2 to 89.7) in the STP group and 86.7% (95% CI, 78.7 to 93.3) and 91.4% (95% CI, 83.6 to 97.1) in the CT group (p=0.512 and p=0.324), respectively. The frequency of adverse effects was higher in the CT group (28.2%) than in the STP group (12.8%) (p=0.002).

conclusionsSTP and CT are encouragingly efficacious as first-line treatments for

Indexed as

Anti-Bacterial AgentsClarithromycinMetronidazoleAdultAgedAmoxicillinDietary SupplementsDrug Therapy, CombinationFemaleHelicobacter InfectionsHelicobacter pyloriHumansMaleMedical Records, Problem-OrientedMiddle AgedProbioticsAmoxicillinAnti-Bacterial AgentsClarithromycinMetronidazoleProton Pump InhibitorsHelicobacter pyloriMetronidazoleProbiotics

Identifiers

PMID29212313
PMCPMC5832341

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.