Evidence map›Paper›PMID 29212248›Full record

ArticleOncotarget2017

Impact of complement component 3/4/5 single nucleotide polymorphisms on renal transplant recipients with antibody-mediated rejection.

Zijie Wang, Haiwei Yang, Miao Guo, Zhijian Han, Jun Tao, Hao Chen, Yuqiu Ge, Ke Wang, Ruoyun Tan, Ji-Fu Wei and 1 more

Open access · diamondAbstract read
In one paragraph

Article in Oncotarget, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.3field-weighted citation impact, top 41% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 4 citations in OpenAlex.

  1. Recent Advances on Biomarkers of Early and Late Kidney Graft Dysfunction.International journal of molecular sciences · 2020
    Review
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 1 institution in 1 country.

Zijie WangDepartment of Urology, Nanjing Medical University First Affiliated Hospital, Nanjing 210029, P.R. China.
Haiwei YangDepartment of Urology, Nanjing Medical University First Affiliated Hospital, Nanjing 210029, P.R. China.
Miao GuoResearch Division of Clinical Pharmacology, Nanjing Medical University First Affiliated Hospital, Nanjing 210029, P.R. China.
Zhijian HanDepartment of Urology, Nanjing Medical University First Affiliated Hospital, Nanjing 210029, P.R. China.
Jun TaoDepartment of Urology, Nanjing Medical University First Affiliated Hospital, Nanjing 210029, P.R. China.
Hao ChenDepartment of Urology, Nanjing Medical University First Affiliated Hospital, Nanjing 210029, P.R. China.
Yuqiu GeSchool of Public Health, Nanjing Medical University, Nanjing 211166, P.R. China.
Ke WangDepartment of Urology, Nanjing Medical University First Affiliated Hospital, Nanjing 210029, P.R. China.
Ruoyun TanDepartment of Urology, Nanjing Medical University First Affiliated Hospital, Nanjing 210029, P.R. China.
Ji-Fu WeiResearch Division of Clinical Pharmacology, Nanjing Medical University First Affiliated Hospital, Nanjing 210029, P.R. China.
Min GuDepartment of Urology, Nanjing Medical University First Affiliated Hospital, Nanjing 210029, P.R. China.
Nanjing Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Antibody-mediated rejection (ABMR) is an important risk of allograft dysfunction in kidney transplantation. The complement system is considered to be associated with the generation of alloreative antibodies and donor-specific antibodies. However, the association of complement single nucleotide polymorphisms (SNPs) with ABMR still remained unclear. Blood samples of 199 renal transplant recipients containing 68 with ABMR and 131 with stable graft function were collected, and analyzed by next-generation sequencing with an established gene panel. High quality readout was obtained in 18

Indexed as

antibody-mediated rejectioncomplementkidney transplantationnext-generation sequencingsingle nucleotide polymorphism

Identifiers

PMID29212248
PMCPMC5706894
OpenAlexW2763228973

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.