Evidence map›Paper›PMID 29212243›Full record

ArticleOncotarget2017

Effects of silencing Rab27a gene on biological characteristics and chemosensitivity of non-small cell lung cancer.

Xia Li, Haiying Wang, Qinggan Ni, Zhiyuan Tang, Jun Ni, Liqin Xu, Hua Huang, Songshi Ni, Jian Feng

Abstract read
In one paragraph

Article in Oncotarget, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Xia LiDepartment of Respiratory, Yancheng Third People's Hospital, Yancheng 224002, Jiangsu, China.
Haiying WangDepartment of Respiratory, Affiliated Hospital of Nantong University, Nantong 226001, Jiangsu, China.
Qinggan NiDepartment of Central Laboratory, Affiliated Hospital of Nantong University, Nantong 226001, Jiangsu, China.
Zhiyuan TangDepartment of Respiratory, Affiliated Hospital of Nantong University, Nantong 226001, Jiangsu, China.
Jun NiDepartment of Rehabilitation, Affiliated Hospital of Nantong University, Nantong 226001, Jiangsu, China.
Liqin XuDepartment of Respiratory, Affiliated Hospital of Nantong University, Nantong 226001, Jiangsu, China.
Hua HuangDepartment of Pathology, Affiliated Hospital of Nantong University, Nantong 226001, Jiangsu, China.
Songshi NiDepartment of Respiratory, Affiliated Hospital of Nantong University, Nantong 226001, Jiangsu, China.
Jian FengDepartment of Respiratory, Affiliated Hospital of Nantong University, Nantong 226001, Jiangsu, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Rab27a, a member of the Rab protein family, can regulate the tumor microenvironment and promote the development of the tumor. Elevated expression of Rab27a is closely connected with many human cancers containing non-small cell lung cancer (NSCLC). But the role of Rab27a in non-small cell lung cancer and its possible mechanism is particularly unclear. In this research, we explored the effect of silencing Rab27a

Indexed as

biological characteristicsmigrationnon-small cell lung cancerproliferationRab27a

Identifiers

PMID29212243
PMCPMC5706889

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.