Evidence map›Paper›PMID 29211900›Full record

ArticleInternational journal of epidemiology2018

Racial/ethnic differences in the epidemiology of ovarian cancer: a pooled analysis of 12 case-control studies.

Lauren C Peres, Harvey Risch, Kathryn L Terry, Penelope M Webb, Marc T Goodman, Anna H Wu, Anthony J Alberg, Elisa V Bandera, Jill Barnholtz-Sloan, Melissa L Bondy and 32 more

Erratum issuedOpen access · bronzeAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in International journal of epidemiology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 29 papers.

0numbers the graph read from it
0cells of the map it votes in
29citing papers in PubMed
3.3field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

29 citing papers in PubMed, 47 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Global epidemiology of epithelial ovarian cancer.Nature reviews. Clinical oncology · 2024
    Review
  8. Article
  9. The Impact of Endometriosis on Pregnancy.Journal of personalized medicine · 2024
    Review
  10. Review
  11. Lymphatic vasculature in ovarian cancer.Biochimica et biophysica acta. Reviews on cancer · 2023
    Review
  12. Prevention of Epithelial Ovarian Cancer.Cold Spring Harbor perspectives in medicine · 2023
    Review
  13. Article
  14. Article
  15. Article
  16. Article
  17. Cohort Profile: The Ovarian Cancer Cohort Consortium (OC3).International journal of epidemiology · 2022
    Article
  18. Review
  19. Genital Powder Use and Risk of Epithelial Ovarian Cancer in the Ovarian Cancer in Women of African Ancestry Consortium.Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology · 2021
    Article
  20. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

42 authors at 20 institutions in 3 countries.

Lauren C PeresDepartment of Public Health Sciences, University of Virginia, Charlottesville, VA, USA.
Harvey RischDepartment of Chronic Disease Epidemiology, Yale School of Public Health, New Haven, CT, USA.
Kathryn L TerryObstetrics and Gynecology Epidemiology Center, Brigham and Women's Hospital, Boston, MA, USA.
Penelope M WebbPopulation Health Department, QIMR Berghofer Medical Research Institute, Brisbane, QLD, Australia.
Marc T GoodmanSamuel Oschin Comprehensive Cancer Institute.
Anna H WuDepartment of Preventive Medicine, University of Southern California Norris Comprehensive Cancer Center, Los Angeles, CA, USA.
Anthony J AlbergHollings Cancer Center, Medical University of South Carolina, Charleston, SC, USA.
Elisa V BanderaCancer Prevention and Control Program, Rutgers Cancer Institute of New Jersey, New Brunswick, NJ, USA.
Jill Barnholtz-SloanCase Comprehensive Cancer Center, Case Western Reserve University School of Medicine, Cleveland, OH, USA.
Melissa L BondyCancer Prevention and Population Sciences Program, Baylor College of Medicine, Houston, TX, USA.
Michele L CoteKarmanos Cancer Institute Population Studies and Disparities Research Program, Wayne State University School of Medicine, Detroit, MI, USA.
Ellen FunkhouserDivision of Preventive Medicine, University of Alabama at Birmingham, Birmingham, AL, USA.
Patricia G MoormanDepartment of Community and Family Medicine, Duke University Medical Center, Durham, NC, USA.
Edward S PetersDepartment of Epidemiology, Louisiana State University Health Sciences Center School of Public Health, New Orleans, LA, USA.
Ann G SchwartzKarmanos Cancer Institute Population Studies and Disparities Research Program, Wayne State University School of Medicine, Detroit, MI, USA.
Paul D TerryGraduate School of Medicine, University of Tennessee Medical Center, Knoxville, TN, USA.
Ani ManichaikulDepartment of Public Health Sciences, University of Virginia, Charlottesville, VA, USA.
Sarah E AbbottDepartment of Public Health Sciences, University of Virginia, Charlottesville, VA, USA.
Fabian CamachoDepartment of Public Health Sciences, University of Virginia, Charlottesville, VA, USA.
Susan J JordanPopulation Health Department, QIMR Berghofer Medical Research Institute, Brisbane, QLD, Australia.
Christina M NaglePopulation Health Department, QIMR Berghofer Medical Research Institute, Brisbane, QLD, Australia.
Australian Ovarian Cancer Study Group
Mary Anne RossingDivision of Public Health Sciences, Fred Hutchinson Cancer Research Center, Seattle, WA, USA.
Jennifer A DohertyHuntsman Cancer Institute, University of Utah, Salt Lake City, UT, USA.
Francesmary ModugnoDepartment of Obstetrics, Gynecology and Reproductive Sciences, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA.
Kirsten MoysichDepartment of Cancer Prevention and Control, Roswell Park Cancer Institute, Buffalo, NY, USA.
Roberta NessUniversity of Texas School of Public Health, Houston, TX, USA.
Andrew BerchuckDepartment of Obstetrics and Gynecology, Duke University Medical Center, Durham, NC, USA.
Linda CookDivision of Epidemiology and Biostatistics, University of New Mexico, Albuquerque, NM, USA.
Nhu LeCancer Control Research.
Angela Brooks-WilsonCanada's Michael Smith Genome Sciences Centre, British Columbia Cancer Agency, Vancouver, BC, Canada.
Weiva SiehDepartment of Population Health Science and Policy and Department of Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
Alice WhittemoreDepartment of Health Research and Policy, Stanford University School of Medicine, Stanford, CA, USA.
Valerie McGuireDepartment of Health Research and Policy, Stanford University School of Medicine, Stanford, CA, USA.
Joseph RothsteinDepartment of Population Health Science and Policy and Department of Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
Hoda Anton-CulverDepartment of Epidemiology.
Argyrios ZiogasDepartment of Epidemiology.
Celeste L PearceDepartment of Preventive Medicine, University of Southern California Norris Comprehensive Cancer Center, Los Angeles, CA, USA.
Chiuchen TsengDepartment of Preventive Medicine, University of Southern California Norris Comprehensive Cancer Center, Los Angeles, CA, USA.
Malcom PikeDepartment of Preventive Medicine, University of Southern California Norris Comprehensive Cancer Center, Los Angeles, CA, USA.
Joellen M SchildkrautDepartment of Public Health Sciences, University of Virginia, Charlottesville, VA, USA.
African American Cancer Epidemiology Study and the Ovarian Cancer Association Consortium
University of Southern California · USUniversity of Virginia · USQIMR Berghofer Medical Research Institute · AUStanford University · USDuke Medical Center · USRoswell Park Comprehensive Cancer Center · USSimon Fraser University · CAUniversity of California, Irvine · USUniversity of New Mexico · USUniversity of Washington · USWayne State University · USBaylor College of Medicine · USBrigham and Women's Hospital · USCase Western Reserve University · USCedars-Sinai Medical Center · USLouisiana State University Health Sciences Center New Orleans · USMedical University of South Carolina · USRutgers, The State University of New Jersey · USUniversity of Alabama at Birmingham · USUniversity of Pittsburgh · US

Funding

X-RAY CRYSTALLOGRAPHYP30CA008748 · NCI · SLOAN-KETTERING INSTITUTE FOR CANCER RES · PI Hongbiao Carl Lekaye · 1985 to 2026
$347.4M
USC/NORRIS COMPREHENSIVE CANCER CENTER (CORE) SUPPORTP30CA014089 · NCI · UNIVERSITY OF SOUTHERN CALIFORNIA · PI MYLES G COCKBURN · 1985 to 2026
$181.4M
Northern California Cooperative Family Registry for Breast CancerU01CA069417 · NCI · NORTHERN CALIFORNIA CANCER CENTER · PI JOHN, ESTHER M. · 1995 to 2010
$22.4M
RPCI-UPCI Ovarian Cancer SPOREP50CA159981 · NCI · ROSWELL PARK CANCER INSTITUTE CORP · PI MOYSICH, KIRSTEN B., ODUNSI, KUNLE · 2013 to 2025
$19.6M
USC CANCER EPIDEMIOLOGY &BIOSTATISTICS UNITP01CA017054 · NCI · UNIVERSITY OF SOUTHERN CALIFORNIA · PI PIKE, MALCOLM C · 1985 to 2009
$18.2M
Novel Serum, Plasma, and Urine Biomarkers of Ovarian CanP50CA105009 · NCI · BRIGHAM AND WOMEN'S HOSPITAL · PI CRAMER, DANIEL WILLIAM · 2004 to 2010
$13.3M
Epidemiology of Ovarian Cancer in African-American WomenR01CA142081 · NCI · UNIVERSITY OF VIRGINIA · PI SCHILDKRAUT, JOELLEN M. · 2010 to 2015
$10.6M
The Molecular Epidemiology Of Ovarian CancerR01CA076016 · NCI · DUKE UNIVERSITY · PI SCHILDKRAUT, JOELLEN M. · 1998 to 2010
$6.2M
OVARIAN CANCER RISK AND HYPERGONADOTROPIC HYPOGONADISMR01CA054419 · NCI · BRIGHAM AND WOMEN'S HOSPITAL · PI CRAMER, DANIEL WILLIAM · 1992 to 2007
$5.9M
COLLABORATIVE STUDY OF OVARIAN CANCER IN TWO RISK GROUPSR01CA058598 · NCI · UNIVERSITY OF HAWAII AT MANOA · PI GOODMAN, MARC T · 1993 to 2012
$4.6M
Steroid Hormone Genes and Ovarian Cancer RiskR01CA112523 · NCI · FRED HUTCHINSON CANCER RESEARCH CENTER · PI ROSSING, MARY ANNE · 2006 to 2010
$3.3M
HEREDITARY BREAST CANCER--GENETIC AND MOLECULAR STUDIESR01CA058860 · NCI · UNIVERSITY OF CALIFORNIA-IRVINE · PI ANTON-CULVER, HODA A · 1994 to 2008
$3.1M
NCI NIH HHS K07 CA080668NCI NIH HHS K07 CA143047NCI NIH HHS N01 CN025403NCI NIH HHS N01 PC067010NCI NIH HHS P01 CA017054NCI NIH HHS P30 CA008748NCI NIH HHS P30 CA014089NCI NIH HHS P50 CA105009NCI NIH HHS P50 CA159981NCI NIH HHS R01 CA054419NCI NIH HHS R01 CA058598NCI NIH HHS R01 CA058860NCI NIH HHS R01 CA074850NCI NIH HHS R01 CA076016NCI NIH HHS R01 CA095023NCI NIH HHS R01 CA112523NCI NIH HHS R01 CA142081NCI NIH HHS R01 CA160669NCI NIH HHS R01 CA207260NCI NIH HHS R03 CA113148NCI NIH HHS R03 CA115195NCI NIH HHS U01 CA069417
6 · The paper itself

Abstract

Background: Ovarian cancer incidence differs substantially by race/ethnicity, but the reasons for this are not well understood. Data were pooled from the African American Cancer Epidemiology Study (AACES) and 11 case-control studies in the Ovarian Cancer Association Consortium (OCAC) to examine racial/ethnic differences in epidemiological characteristics with suspected involvement in epithelial ovarian cancer (EOC) aetiology. Methods: We used multivariable logistic regression to estimate associations for 17 reproductive, hormonal and lifestyle characteristics and EOC risk by race/ethnicity among 10 924 women with invasive EOC (8918 Non-Hispanic Whites, 433 Hispanics, 911 Blacks, 662 Asian/Pacific Islanders) and 16 150 controls (13 619 Non-Hispanic Whites, 533 Hispanics, 1233 Blacks, 765 Asian/Pacific Islanders). Likelihood ratio tests were used to evaluate heterogeneity in the risk factor associations by race/ethnicity. Results: We observed statistically significant racial/ethnic heterogeneity for hysterectomy and EOC risk (P = 0.008), where the largest odds ratio (OR) was observed in Black women [OR = 1.64, 95% confidence interval (CI) = 1.34-2.02] compared with other racial/ethnic groups. Although not statistically significant, the associations for parity, first-degree family history of ovarian or breast cancer, and endometriosis varied by race/ethnicity. Asian/Pacific Islanders had the greatest magnitude of association for parity (≥3 births: OR = 0.38, 95% CI = 0.28-0.54), and Black women had the largest ORs for family history (OR = 1.77, 95% CI = 1.42-2.21) and endometriosis (OR = 2.42, 95% CI = 1.65-3.55). Conclusions: Although racial/ethnic heterogeneity was observed for hysterectomy, our findings support the validity of EOC risk factors across all racial/ethnic groups, and further suggest that any racial/ethnic population with a higher prevalence of a modifiable risk factor should be targeted to disseminate information about prevention.

Indexed as

AdolescentAdultAgedAged, 80 and overCarcinoma, Ovarian EpithelialCase-Control StudiesEthnicityFemaleHumansIncidenceMiddle AgedMultivariate AnalysisOvarian NeoplasmsParityPregnancyPrevalence

Identifiers

PMID29211900
PMCPMC5913601
OpenAlexW2791921535

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.