Evidence map›Paper›PMID 29211713›Full record

ArticleNature2017

Runx3 programs CD8

J Justin Milner, Clara Toma, Bingfei Yu, Kai Zhang, Kyla Omilusik, Anthony T Phan, Dapeng Wang, Adam J Getzler, Toan Nguyen, Shane Crotty and 3 more

Erratum issuedAbstract read
In one paragraph

Article in Nature, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 483 papers.

0numbers the graph read from it
0cells of the map it votes in
483citing papers in PubMed
21.6field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

483 citing papers in PubMed, 657 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Monocyte-derived galectin-1Nature immunology · 2026
    Article
  5. Review
  6. Article
  7. A Gene-Program Architecture of Mouse T cells.bioRxiv : the preprint server for biology · 2026
    Article
  8. Article
  9. Article
  10. Article
  11. Review
  12. A pathogenic CD8⁺ TNature communications · 2026
    Article
  13. Article
  14. Article
  15. Article
  16. CD8MedComm · 2026
    Review
  17. Article
  18. Article
  19. Article
  20. Article

423 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

13 authors at 3 institutions in 1 country.

J Justin MilnerDivision of Biological Sciences, University of California, San Diego, La Jolla, California, USA.
Clara TomaDivision of Biological Sciences, University of California, San Diego, La Jolla, California, USA.
Bingfei YuDivision of Biological Sciences, University of California, San Diego, La Jolla, California, USA.
Kai ZhangBioinformatics and Systems Biology Graduate Program, University of California, San Diego, La Jolla, California, USA.
Kyla OmilusikDivision of Biological Sciences, University of California, San Diego, La Jolla, California, USA.
Anthony T PhanDivision of Biological Sciences, University of California, San Diego, La Jolla, California, USA.
Dapeng WangDepartment of Immunology and Microbiology, The Scripps Research Institute, Jupiter, Florida, USA.
Adam J GetzlerDepartment of Immunology and Microbiology, The Scripps Research Institute, Jupiter, Florida, USA.
Toan NguyenDivision of Biological Sciences, University of California, San Diego, La Jolla, California, USA.
Shane CrottyDivision of Vaccine Discovery, La Jolla Institute for Allergy and Immunology, La Jolla, California, USA.
Wei WangBioinformatics and Systems Biology Graduate Program, University of California, San Diego, La Jolla, California, USA.
Matthew E PipkinDepartment of Immunology and Microbiology, The Scripps Research Institute, Jupiter, Florida, USA.
Ananda W GoldrathDivision of Biological Sciences, University of California, San Diego, La Jolla, California, USA.
University of California, San Diego · USScripps Research Institute · USLa Jolla Institute for Immunology · US

Funding

TF regulation of CD8 and CD4 T cell memory in both systemic and dermal infectionU19AI109976 · NIAID · LA JOLLA INSTITUTE FOR IMMUNOLOGY · PI PETERS, BJOERN · 2014 to 2018
$10.5M
Integrated analysis of genetic variation and epigenomic dataR01HG009626 · NHGRI · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI WANG, WEI · 2017 to 2025
$4.5M
T cell maintenance: molecular mediators of T cell differentiation and survivalR37AI067545 · NIAID · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI Ananda W Goldrath · 2022 to 2026
$3.0M
Regulation of nucleosome positions and transcription during CTL differentiationR01AI095634 · NIAID · SCRIPPS FLORIDA · PI PIPKIN, MATTHEW EUGENE · 2011 to 2015
$2.4M
Illumina HiSeq 2500 Sequencing SystemS10OD016262 · OD · LA JOLLA INSTITUTE FOR IMMUNOLOGY · PI RAO, ANJANA · 2013 to 2013
$600k
FACSAria II Cell SorterS10RR027366 · NCRR · LA JOLLA INSTITUTE FOR IMMUNOLOGY · PI CROFT, MICHAEL · 2011 to 2011
$514k
NHGRI NIH HHS R01 HG009626NIAID NIH HHS R01 AI095634NIAID NIH HHS R37 AI067545NIAID NIH HHS U19 AI109976NIH HHS S10 OD016262
6 · The paper itself

Abstract

Tissue-resident memory CD8

Indexed as

Immunologic MemoryAdoptive TransferAnimalsCD8-Positive T-LymphocytesCell DifferentiationCell ProliferationChromatinCore Binding Factor Alpha 3 SubunitDisease Models, AnimalFemaleGene Expression RegulationHomeostasisHumansLymphocytes, Tumor-InfiltratingMaleMelanomaChromatinCore Binding Factor Alpha 3 SubunitRunx3 protein, mouse

Identifiers

PMID29211713
PMCPMC5747964
OpenAlexW2774264760

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.