ArticleJournal of cognitive neuroscience2018
Selective Interference with Syntactic Encoding during Sentence Production by Direct Electrocortical Stimulation of the Inferior Frontal Gyrus.
Article in Journal of cognitive neuroscience, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
28 citing papers in PubMed, 1 synthesis or guideline pooled it.
- The Neurofunctional Correlates of Morphosyntactic and Thematic Impairments in Aphasia: A Systematic Review and Meta-analysis.Neuropsychology review · 2025Pooled it
- Aperiodic Dynamics of Cell Assemblies Recruited for L1 and L2 Processing of FrenchBrain sciences · 2026Article
- Causal parametric language mapping with electrical stimulation during awake neurosurgery.Science advances · 2026Article
- Neural activity flows through cortical subnetworks during speech production.Cell reports · 2026Article
- Speech sequencing in the human precentral gyrus.Nature human behaviour · 2025Article
- Temporoparietal brain structures support sentence processing across the adult lifespan.Imaging neuroscience (Cambridge, Mass.) · 2025Article
- The speech neuroprosthesis.Nature reviews. Neuroscience · 2024Review
- Stimulation of caudal inferior and middle frontal gyri disrupts planning during spoken interaction.Current biology : CB · 2024Article
- A modified neural circuit framework for semantic memory retrieval with implications for circuit modulation to treat verbal retrieval deficits.Brain and behavior · 2024Review
- The language network as a natural kind within the broader landscape of the human brain.Nature reviews. Neuroscience · 2024Review
- Discriminating nonfluent/agrammatic and logopenic PPA variants with automatically extracted morphosyntactic measures from connected speech.Cortex; a journal devoted to the study of the nervous system and behavior · 2024Article
- Neural basis of speech and grammar symptoms in non-fluent variant primary progressive aphasia spectrum.Brain : a journal of neurology · 2024Article
- Evaluating syntactic comprehension during awake intraoperative cortical stimulation mapping.Journal of neurosurgery · 2023Article
- Intra- and inter-hemispheric network dynamics supporting object recognition and speech production.NeuroImage · 2023Article
- Neuroplasticity in F16 fighter jet pilots.Frontiers in physiology · 2023Article
- A Neurosurgical Functional Dissection of the Middle Precentral Gyrus during Speech Production.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2022Review
- The Use of Standardized Intraoperative Language Tests in Awake Craniotomies: A Scoping Review.Neuropsychology review · 2022Article
- Functional maps of direct electrical stimulation-induced speech arrest and anomia: a multicentre retrospective study.Brain : a journal of neurology · 2021Article
- A Review of Cortical and Subcortical Stimulation Mapping for Language.Neurosurgery · 2021Review
- Clinical Pearls and Methods for Intraoperative Awake Language Mapping.Neurosurgery · 2021Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
Abstract
Cortical stimulation mapping (CSM) has provided important insights into the neuroanatomy of language because of its high spatial and temporal resolution, and the causal relationships that can be inferred from transient disruption of specific functions. Almost all CSM studies to date have focused on word-level processes such as naming, comprehension, and repetition. In this study, we used CSM to identify sites where stimulation interfered selectively with syntactic encoding during sentence production. Fourteen patients undergoing left-hemisphere neurosurgery participated in the study. In 7 of the 14 patients, we identified nine sites where cortical stimulation interfered with syntactic encoding but did not interfere with single word processing. All nine sites were localized to the inferior frontal gyrus, mostly to the pars triangularis and opercularis. Interference with syntactic encoding took several different forms, including misassignment of arguments to grammatical roles, misassignment of nouns to verb slots, omission of function words and inflectional morphology, and various paragrammatic constructions. Our findings suggest that the left inferior frontal gyrus plays an important role in the encoding of syntactic structure during sentence production.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.