Evidence map›Paper›PMID 29211027›Full record

ArticleNutrients2017

Dietary Intake of Protein from Different Sources and Weight Regain, Changes in Body Composition and Cardiometabolic Risk Factors after Weight Loss: The DIOGenes Study.

Marleen A van Baak, Thomas M Larsen, Susan A Jebb, Alfredo Martinez, Wim H M Saris, Teodora Handjieva-Darlenska, Anthony Kafatos, Andreas F H Pfeiffer, Marie Kunešová, Arne Astrup

Open access · goldAbstract read
In one paragraph

Article in Nutrients, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed, 2 pooled it
2.3field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 2 syntheses or guidelines pooled it, 38 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 8 institutions in 8 countries.

Marleen A van BaakDepartment of Human Biology, NUTRIM School for Nutrition and Translational Research in Metabolism, Maastricht University Medical Centre, 6200MD Maastricht, The Netherlands. m.vanbaak@maastrichtuniversity.nl.ORCID 0000-0003-2592-6363
Thomas M LarsenDepartment of Nutrition, Exercise and Sports (NEXS), Faculty of Science, University of Copenhagen, 2200 Copenhagen, Denmark. tml@life.ku.dk.ORCID 0000-0001-7621-3131
Susan A JebbNuffield Department of Primary Care Health Sciences, University of Oxford, Oxford OX2 6GG, UK. susan.jebb@phc.ox.ac.uk.
Alfredo MartinezDepartment of Physiology and Nutrition, University of Navarra, 31008 Pamplona, Spain. jalfmtz@unav.es.ORCID 0000-0001-5218-6941
Wim H M SarisDepartment of Human Biology, NUTRIM School for Nutrition and Translational Research in Metabolism, Maastricht University Medical Centre, 6200MD Maastricht, The Netherlands. w.saris@maastrichtuniversity.nl.
Teodora Handjieva-DarlenskaDepartment of Pharmacology and Toxicology, Faculty of Medicine, Medical University, 1000 Sofia, Bulgaria. teodorah@abv.bg.
Anthony KafatosDepartment of Social Medicine, Preventive Medicine & Nutrition Clinic, University of Crete, 71003 Heraklion, Greece. kafatos@med.uoc.gr.
Andreas F H PfeifferDepartment of Clinical Nutrition, German Institute of Human Nutrition Potsdam-Rehbrücke, 14558 Nuthetal, Germany. afhp@dife.de.ORCID 0000-0002-6887-0016
Marie KunešováObesity Management Center, Institute of Endocrinology, 11694 Prague, Czech Republic. mkunesova@endo.cz.
Arne AstrupDepartment of Nutrition, Exercise and Sports (NEXS), Faculty of Science, University of Copenhagen, 2200 Copenhagen, Denmark. ast@life.ku.dk.
Maastricht University Medical Centre · NLUniversity of Copenhagen · DKGerman Institute of Human Nutrition · DEInstitute of Endocrinology · CZMedical University of Sofia · BGUniversidad de Navarra · ESUniversity of Crete · GRUniversity of Oxford · GB

Funding

Medical Research Council MC_U105960389
6 · The paper itself

Abstract

An increase in dietary protein intake has been shown to improve weight loss maintenance in the DIOGenes trial. Here, we analysed whether the source of the dietary proteins influenced changes in body weight, body composition, and cardiometabolic risk factors during the weight maintenance period while following an energy-restricted diet. 489 overweight or obese participants of the DIOGenes trial from eight European countries were included. They successfully lost >8% of body weight and subsequently completed a six month weight maintenance period, in which they consumed an ad libitum diet varying in protein content and glycemic index. Dietary intake was estimated from three-day food diaries. A higher plant protein intake with a proportional decrease in animal protein intake did not affect body weight maintenance or cardiometabolic risk factors. A higher plant protein intake from non-cereal products instead of cereal products was associated with benefits for body weight maintenance and blood pressure. Substituting meat protein for protein from other animal sources increased insulin and HOMA-IR (homeostasis model assessment of insulin resistance). This analysis suggests that not only the amount of dietary proteins, but also the source may be important for weight and cardiometabolic risk management. However, randomized trials are needed to test the causality of these associations.

Indexed as

Body CompositionBody WeightFood AnalysisAdultBody Weight MaintenanceDietary ProteinsDiet, ReducingEnergy IntakeFemaleHumansMaleRisk FactorsWeight GainWeight LossDietary Proteinsanimal proteincardiometabolic risk factorscereal proteindietmeat proteinobesityplant proteinprotein sourcesweight loss maintenance

Identifiers

PMID29211027
PMCPMC5748776
OpenAlexW2774084948

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.