ArticleRetina (Philadelphia, Pa.)2018
COMBINED AUTOLOGOUS TRANSPLANTATION OF NEUROSENSORY RETINA, RETINAL PIGMENT EPITHELIUM, AND CHOROID FREE GRAFTS.
Article in Retina (Philadelphia, Pa.), 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03798145 (Surgical Retinotomy for the Treatment of Glaucoma), which is not on this map. Cited by 7 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Surgical Retinotomy for the Treatment of Glaucoma
Who cites it
7 citing papers in PubMed, 27 citations in OpenAlex.
- Autologous retina transplantation for refractory highly myopic macular holes: a long-term follow-up.Japanese journal of ophthalmology · 2025Article
- Large macular hole and autologous retinal transplantation: a systematic review and meta-analysis.International journal of retina and vitreous · 2024Review
- Logbook of a Retinal Autograft.Turkish journal of ophthalmology · 2022Article
- Applications of the Amniotic Membrane in Vitreoretinal Surgery.Journal of clinical medicine · 2020Review
- Management of refractory macular hole with blood and gas-assisted autologous neurosensory retinal free flap transplantation: a case report.BMC ophthalmology · 2018Article
- Current management strategies for atypical macular holes.Taiwan journal of ophthalmologyReview
- Autologous Neurosensory Retinal Flap Transplantation in a Porcine Model of Retinal Hole.Ophthalmology scienceArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
9 authors at 1 institution in 1 country.
Funding
Abstract
purposeTo evaluate the feasibility and initial functional and anatomical outcomes of transplanting a full-thickness free graft of choroid and retinal pigment epithelium (RPE), along with neurosensory retina in advanced fibrosis and atrophy associated with end-stage exudative age-related macular degeneration with and without a concurrent refractory macular hole.
methodsDuring vitrectomy, an RPE-choroidal and neurosensory retinal free graft was harvested in nine eyes of nine patients. The RPE-choroidal and neurosensory retinal free graft was either placed subretinally (n = 5), intraretinally to cover the foveal area inside an iatrogenically induced macular hole over the RPE-choroidal graft (n = 3) or preretinally (n = 1) without a retinotomy wherein both free grafts were placed over the concurrent macular hole. Silicone oil endotamponade was used in all cases.
resultsMean follow-up was 7 ± 5.5 months (range 3-19). The mean preoperative visual acuity was ∼count fingers (logarithm of the minimum angle of resolution = 2.11, range 2-3), which improved to ∼20/800 (logarithm of the minimum angle of resolution 1.62 ± 0.48, range 0.7-2, P = 0.04). Vision was stable in 5 eyes (55.6%) and improved in 4 eyes (44.4%). Reading ability improved in 5 eyes (55.6%). Postoperative complications were graft atrophy (n = 1), epiretinal membrane (n = 1), and dislocation of neurosensory retina-choroid-RPE free graft (n = 1).
conclusionCombined autologous RPE-choroid and neurosensory retinal free graft is a potential surgical alternative in eyes with end-stage exudative age-related macular degeneration, including concurrent refractory macular hole.
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