Evidence map›Paper›PMID 29210826›Full record

ArticleJournal of acquired immune deficiency syndromes (1999)2018

High Acceptability and Increased HIV-Testing Frequency After Introduction of HIV Self-Testing and Network Distribution Among South African MSM.

Sheri A Lippman, Tim Lane, Oscar Rabede, Hailey Gilmore, Yea-Hung Chen, Nkuli Mlotshwa, Kabelo Maleke, Alexander Marr, James A McIntyre

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of acquired immune deficiency syndromes (1999), 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 106 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
106citing papers in PubMed, 4 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

106 citing papers in PubMed, 4 syntheses or guidelines pooled it.

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46 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Sheri A LippmanCenter for AIDS Prevention Studies, University of California, San Francisco, San Francisco, CA.
Tim LaneCenter for AIDS Prevention Studies, University of California, San Francisco, San Francisco, CA.
Oscar RabedeDepartment of Medicine, Anova Health Institute, Johannesburg, South Africa.
Hailey GilmoreCenter for AIDS Prevention Studies, University of California, San Francisco, San Francisco, CA.
Yea-Hung ChenCenter for Public Health Research, San Francisco Department of Public Health, San Francisco, CA.
Nkuli MlotshwaDepartment of Medicine, Anova Health Institute, Johannesburg, South Africa.
Kabelo MalekeDepartment of Medicine, Anova Health Institute, Johannesburg, South Africa.
Alexander MarrCenter for AIDS Prevention Studies, University of California, San Francisco, San Francisco, CA.
James A McIntyreDepartment of Medicine, Anova Health Institute, Johannesburg, South Africa.

Funding

Ujima Mentoring ProgramP30MH062246 · NIMH · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI Sheri Ann Lippman · 2001 to 2026
$57.4M
Self-Conducted HIV Tests - Improving HIV Prevention in Key PopulationsR21MH103038 · NIMH · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI LIPPMAN, SHERI ANN · 2014 to 2016
$486k
NIMH NIH HHS P30 MH062246NIMH NIH HHS R21 MH103038
6 · The paper itself

Abstract

backgroundSouth African men who have sex with men (MSM) have a high burden of undiagnosed HIV infection and HIV-testing rates incommensurate with their risk. HIV self-testing (HIVST) may increase testing uptake, frequency, and earlier HIV detection and treatment.

settingGert Sibande and Ehlanzeni districts, Mpumalanga Province, South Africa.

methodsWe conducted a longitudinal HIVST study among MSM between June 2015 and May 2017. Overall 127 HIV-negative MSM were provided with up to 9 test kits of their choice-oral fluid or blood fingerstick-to use themselves and distribute to their networks. Surveys conducted 3- and 6-month post-enrollment elicited information on HIVST experiences, preferences, acceptability, utilization, and distribution. We used generalized estimating equations to assess changes in testing frequency.

resultsNinety-one percent of participants self-tested. All participants who self-tested reported being likely to self-test again, with over 80% preferring HIVST to clinic-based testing. Fingerstick was preferred to oral fluid tests by approximately 2:1. Returning participants distributed 728 tests to sexual partners (18.5% of kits), friends (51.6%), and family (29.8%). Six participants seroconverted during the study, and 40 new diagnoses were reported among test recipients. Frequent (semi-annual) testing increased from 37.8% before the study to 84.5% at follow-up (P < 0.001), and participants reported anticipated frequent testing of 100% if HIVST were available compared with 84% if only clinic-testing were available in the coming year (P < 0.01).

conclusionsHIVST use and network distribution is acceptable and feasible for MSM in South Africa and can increase testing uptake and frequency, potentially improving early detection among MSM and their networks.

Indexed as

Homosexuality, MalePatient Acceptance of Health CareAdolescentAdultDiagnostic Tests, RoutineFemaleHIV InfectionsHumansLongitudinal StudiesMaleMass ScreeningSelf-ExaminationSocial NetworkingSouth AfricaYoung Adult

Identifiers

PMID29210826
PMCPMC5807184

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.