ArticleAnesthesia and analgesia2018
Management of 1-Lung Ventilation-Variation and Trends in Clinical Practice: A Report From the Multicenter Perioperative Outcomes Group.
Article in Anesthesia and analgesia, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
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Who cites it
13 citing papers in PubMed, 26 citations in OpenAlex.
- [Effects ofNan fang yi ke da xue xue bao = Journal of Southern Medical University · 2024Trial
- Review
- Intraoperative mechanical power and postoperative pulmonary complications: association and threshold analysis in adult intra-abdominal surgery.Journal of anesthesia, analgesia and critical care · 2026Article
- Intraoperative Hemodynamic Management During Esophagectomy and Implications for Postoperative Care.Journal of the American College of Surgeons · 2026Article
- Higher vs. lower positive end-expiratory pressure during one-lung ventilation for thoracic surgery: a systematic review and meta-analysis.Frontiers in surgery · 2026Review
- Postoperative outcomes following anatomical lung resections in relation to intraoperative ventilation practices: a registry-based multicenter study.Frontiers in surgery · 2026Article
- Article
- Impact of intraoperative ventilation parameters on postoperative outcomes in thoracic surgery: a multicenter registry-based analysis.Frontiers in surgery · 2025Article
- Time-of-day dependent effects of midazolam administration on myocardial injury in non-cardiac surgery.Frontiers in cardiovascular medicine · 2022Article
- A Lower Tidal Volume Regimen during One-lung Ventilation for Lung Resection Surgery Is Not Associated with Reduced Postoperative Pulmonary Complications.Anesthesiology · 2021Observational
- Intraoperative mechanical ventilation practice in thoracic surgery patients and its association with postoperative pulmonary complications: results of a multicenter prospective observational study.BMC anesthesiology · 2020Observational
- Improved Compliance With Anesthesia Quality Measures After Implementation of Automated Monthly Feedback.Journal of oncology practice · 2019Article
- Anaesthesia management for bronchoscopic and surgical lung volume reduction.Journal of thoracic disease · 2018Review
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Authors and funding
8 authors at 3 institutions in 1 country.
Funding
Abstract
backgroundLung-protective ventilation (LPV) has been demonstrated to improve clinical outcomes in surgical patients. There are very limited data on the current use of LPV for patients undergoing 1-lung ventilation (1LV) despite evidence that 1LV may be a particularly important setting for its use. In this multicenter study, we report trends in ventilation practice for patients undergoing 1LV.
methodsThe Multicenter Perioperative Outcomes Group database was used to identify patients undergoing 1LV. We retrieved and calculated median initial and overall tidal volume (VT) for the cohort and for high-risk subgroups (female sex, obesity [body mass index >30 kg/m], and short stature), percentage of patients receiving positive end-expiratory pressure (PEEP) ≥5 cm H2O, LPV during 1LV (VT ≤ 6 mL/kg predicted body weight [PBW] and PEEP ≥5 cm H2O), and ventilator driving pressure (ΔP; plateau airway pressure - PEEP).
resultsData from 5609 patients across 4 institutions were included in the analysis. Median VT was calculated for each case and since the data were normally distributed, the mean is reported for the entire cohort and subgroups. Mean of median VT during 1LV for the cohort was 6.49 ± 1.82 mL/kg PBW. VT (mL/kg PBW) for high-risk subgroups was significantly higher; 6.86 ± 1.97 for body mass index ≥30 kg/m, 7.05 ± 1.92 for female patients, and 7.33 ± 2.01 for short stature patients. Mean of the median VT declined significantly over the study period (from 6.88 to 5.72; P < .001), and the proportion of patients receiving LPV increased significantly over the study period (from 9.1% to 54.6%; P < .001). These changes coincided with a significant decrease in ΔP during the study period, from 19.4 cm H2O during period 1 to 17.3 cm H2O in period 12 (P = .003).
conclusionsDespite a growing awareness of the importance of protective ventilation, a large proportion of patients undergoing 1LV continue to receive VT PEEP levels outside of recommended thresholds. Moreover, VT remains higher and LPV less common in high-risk subgroups, potentially placing them at elevated risk for iatrogenic lung injury.
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