Evidence map›Paper›PMID 29210527›Full record

ArticleHelicobacter2018

Seroprevalence of Helicobacter pylori in Hispanics living in Puerto Rico: A population-based study.

María González-Pons, Marievelisse Soto-Salgado, Javier Sevilla, Juan M Márquez-Lespier, Douglas Morgan, Cynthia M Pérez, Marcia Cruz-Correa

Open access · hybridAbstract read
In one paragraph

Article in Helicobacter, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
2.0field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 17 citations in OpenAlex.

  1. Trial
  2. Trial
  3. Potential Exposure to Environmental Toxic Emissions and Increased Cancer Risk in Puerto Rico.Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology · 2025
    Article
  4. Article
  5. Article
  6. Helicobacter pylori and Gallstone Disease: Incidence and Outcomes in a Los Angeles County Population.Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract · 2021
    Article
  7. Article
  8. Article
  9. Article
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 2 countries.

María González-PonsUniversity of Puerto Rico Comprehensive Cancer Center, San Juan, Puerto Rico.ORCID http://orcid.org/0000-0002-3694-0534
Marievelisse Soto-SalgadoUniversity of Puerto Rico Medical Sciences Campus, San Juan, Puerto Rico.
Javier SevillaUniversity of Puerto Rico Rio Piedras Campus, San Juan, Puerto Rico.
Juan M Márquez-LespierUniversity of Puerto Rico Medical Sciences Campus, San Juan, Puerto Rico.
Douglas MorganVanderbilt University Medical Center, Nashville, TN, USA.
Cynthia M PérezUniversity of Puerto Rico Medical Sciences Campus, San Juan, Puerto Rico.
Marcia Cruz-CorreaUniversity of Puerto Rico Comprehensive Cancer Center, San Juan, Puerto Rico.
University of Puerto Rico, Medical Sciences Campus · PRUniversity of Puerto Rico at Río Piedras · PRVanderbilt University Medical Center · US

Funding

UPR/MDACC Partnership for Excellence in Cancer Research(Parent Grant U54 CA096297)U54CA096297 · NCI · UNIVERSITY OF PUERTO RICO MED SCIENCES · PI Ilka C Rios · 2002 to 2026
$36.9M
Translational Analysis CoreP30DK058404 · NIDDK · VANDERBILT UNIVERSITY MEDICAL CENTER · PI RICHARD M. PEEK · 2002 to 2026
$29.9M
UPR/MDACC Partnership for Excellence in Cancer Research (Luis Segarra supplement)U54CA096300 · NCI · UNIVERSITY OF TX MD ANDERSON CAN CTR · PI Larkin Strong · 2002 to 2026
$23.8M
TECHNOLOGIES AND RESOURCES FOR CORE LABORATORIESU54MD007587 · NIMHD · UNIVERSITY OF PUERTO RICO MED SCIENCES · PI LUCIANO, CARLOS A., WOJNA, VALERIE · 2012 to 2018
$23.2M
Project 3 - Molecular Signatures of Gastric Carcinogenesis in the Host Response to H. pyloriP01CA028842 · NCI · VANDERBILT UNIVERSITY MEDICAL CENTER · PI WILSON, KEITH T. · 1985 to 2019
$15.8M
NCI NIH HHS P01 CA028842NCI NIH HHS U54 CA096297NCI NIH HHS U54 CA096300NIDDK NIH HHS P30 DK058404NIMHD NIH HHS U54 MD007587
6 · The paper itself

Abstract

backgroundHelicobacter pylori is an important etiologic factor for peptic ulcers and gastric cancer, one of the top ten leading causes of cancer death in Puerto Rico. However, the prevalence of H. pylori infections in this population was previously unknown. The aim of this study was to examine the seroprevalence of H. pylori and its associated risk factors in Puerto Rico. MATERIALS AND

methodsA cross-sectional study was designed using an existing population-based biorepository. Seropositivity was determined using the Premier

resultsA total of 528 population-based serum samples were analyzed. The mean age of the study population was 41 ± 12 years, of whom 55.3% were females. The overall seroprevalence of H. pylori was 33.0% (95% CI = 28.3%-38.1%). Increasing age and having <12 years of education were significantly (P < .05) associated with H. pylori seropositivity in the multivariable model; however, residing in counties with low population density reached marginal significance (P = .085).

conclusionsWe report that H. pylori infection is common among Hispanics living in Puerto Rico. The H. pylori seroprevalence observed in Puerto Rico is similar to the seroprevalence reported in the overall population of the United States. The association between H. pylori seroprevalence and the risk factors analyzed offers insight into the epidemiology of gastric cancer in Puerto Rico and warrants further investigation.

Indexed as

Helicobacter pyloriAdultAge FactorsAntibodies, BacterialCross-Sectional StudiesFemaleHelicobacter InfectionsHispanic or LatinoHumansImmunoglobulin GMaleMiddle AgedPuerto RicoRisk FactorsRural PopulationSeroepidemiologic StudiesAntibodies, BacterialImmunoglobulin Gbirth cohort effectHelicobacter pyloriHelicobacter pylori seropositivityHelicobacter pylori seroprevalenceHispanicPopulation-based

Identifiers

PMID29210527
PMCPMC5814898
OpenAlexW2772385559

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.