Evidence map›Paper›PMID 29210329›Full record

SynthesisThe Physician and sportsmedicine2018

A concise evidence-based physical examination for diagnosis of acromioclavicular joint pathology: a systematic review.

Michael K Krill, Samuel Rosas, KiHyun Kwon, Andrew Dakkak, Benedict U Nwachukwu, Frank McCormick

Registry-linked trialAbstract readSystematic Review
In one paragraph

Synthesis in The Physician and sportsmedicine, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05161468 (Bayesian Non-inferiority Trial of Injection Therapies for Acromioclavicular Joint Pain), which is not on this map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05161468 phase4terminatednot on this mapstarted 2021, after this paper: background citation

Bayesian Non-inferiority Trial of Injection Therapies for Acromioclavicular Joint Pain: a Randomized Clinical Trial

TypeinterventionalSponsorBrooke Army Medical CenterRan2021 to 2025Enrolled34ConditionsAcromioclavicular SprainArmsLidocaine injection, Corticosteroid Injection, Protein Rich Plasma(PRP) Injection
3 · Its place in the literature

Who cites it

10 citing papers in PubMed.

  1. Review
  2. Review
  3. Article
  4. Review
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  8. Review
  9. Article
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Michael K Krilla Florida Atlantic University Charles E. Schmidt College of Medicine , Boca Raton , FL , USA.
Samuel Rosasc Baptist Health, Department of Orthopedic Surgery , Wake Forest University , Winston-Salem , NC , USA.ORCID 0000-0002-7330-3753
KiHyun Kwond Florida International University Herbert Wertheim College of Medicine , Miami , FL , USA.
Andrew Dakkaka Florida Atlantic University Charles E. Schmidt College of Medicine , Boca Raton , FL , USA.
Benedict U Nwachukwue Department of Orthopedic Surgery , Hospital for Special Surgery , New York , NY , USA.
Frank McCormickf Department of Orthopedics , Harvard Medical School, Beth Israel Deaconess Medical Center , Boston , MA , USA.

Funding

Integrative Training in Trauma and Regenerative MedicineT32GM099606 · NIGMS · WAKE FOREST UNIVERSITY HEALTH SCIENCES · PI HOTH, JAMES JASON · 2013 to 2017
$1.0M
NIGMS NIH HHS T32 GM099606
6 · The paper itself

Abstract

objectivesThe clinical examination of the shoulder joint is an undervalued diagnostic tool for evaluating acromioclavicular (AC) joint pathology. Applying evidence-based clinical tests enables providers to make an accurate diagnosis and minimize costly imaging procedures and potential delays in care. The purpose of this study was to create a decision tree analysis enabling simple and accurate diagnosis of AC joint pathology.

methodsA systematic review of the Medline, Ovid and Cochrane Review databases was performed to identify level one and two diagnostic studies evaluating clinical tests for AC joint pathology. Individual test characteristics were combined in series and in parallel to improve sensitivities and specificities. A secondary analysis utilized subjective pre-test probabilities to create a clinical decision tree algorithm with post-test probabilities.

resultsThe optimal special test combination to screen and confirm AC joint pathology combined Paxinos sign and O'Brien's Test, with a specificity of 95.8% when performed in series; whereas, Paxinos sign and Hawkins-Kennedy Test demonstrated a sensitivity of 93.7% when performed in parallel. Paxinos sign and O'Brien's Test demonstrated the greatest positive likelihood ratio (2.71); whereas, Paxinos sign and Hawkins-Kennedy Test reported the lowest negative likelihood ratio (0.35).

conclusionNo combination of special tests performed in series or in parallel creates more than a small impact on post-test probabilities to screen or confirm AC joint pathology. Paxinos sign and O'Brien's Test is the only special test combination that has a small and sometimes important impact when used both in series and in parallel. Physical examination testing is not beneficial for diagnosis of AC joint pathology when pretest probability is unequivocal. In these instances, it is of benefit to proceed with procedural tests to evaluate AC joint pathology. Ultrasound-guided corticosteroid injections are diagnostic and therapeutic. An ultrasound-guided AC joint corticosteroid injection may be an appropriate new standard for treatment and surgical decision-making. LEVEL OF EVIDENCE: II - Systematic Review.

Indexed as

Acromioclavicular JointAlgorithmsHumansPhysical ExaminationSensitivity and SpecificityShoulder JointShoulder PainAcromioclavicular jointdiagnosispathologyphysical examinationshoulder examinationspecial tests

Identifiers

PMID29210329
PMCPMC6396285

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.