ArticleMicrocirculation (New York, N.Y. : 1994)2018
Hyperoxia does not affect oxygen delivery in healthy volunteers while causing a decrease in sublingual perfusion.
Article in Microcirculation (New York, N.Y. : 1994), 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
9 citing papers in PubMed, 15 citations in OpenAlex.
- Trial
- Changes in pulse wave transit time variability after interscalene brachial plexus block placement.Korean journal of anesthesiology · 2026Article
- The correlation study between post-surgery oxygen partial pressure level and prognosis of patients with sepsis during hospitalization.Medicine · 2025Observational
- Hyperoxemia and hypoxemia impair cellular oxygenation: a study in healthy volunteers.Intensive care medicine experimental · 2024Article
- Comparison of sublingual microcirculatory parameters measured by sidestream darkfield videomicroscopy in anesthetized pigs and adult humans.Animal models and experimental medicine · 2023Article
- Brain BOLD and NIRS response to hyperoxic challenge in sickle cell disease and chronic anemias.Magnetic resonance imaging · 2023Article
- Revisited Hyperoxia Pathophysiology in the Perioperative Setting: A Narrative Review.Frontiers in medicine · 2021Review
- Effects of Normoxia, Hyperoxia, and Mild Hypoxia on Macro-Hemodynamics and the Skeletal Muscle Microcirculation in Anesthetised Rats.Frontiers in medicine · 2021Article
- Hyperoxia does not affect oxygen delivery in healthy volunteers while causing a decrease in sublingual perfusion.Microcirculation (New York, N.Y. : 1994) · 2018Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
10 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveTo determine the human dose-response relationship between a stepwise increase in arterial oxygen tension and its associated changes in DO
methodsFifteen healthy volunteers breathed increasing oxygen fractions for 10 minutes to reach arterial oxygen tensions of baseline (breathing air), 20, 40, 60 kPa, and max kPa (breathing oxygen). Systemic hemodynamics were measured continuously by the volume-clamp method. At the end of each period, the sublingual microcirculation was assessed by SDF.
resultsSystemic DO
conclusionsIn healthy volunteers, supraphysiological arterial oxygen tensions have no effect on systemic DO
Indexed as
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.