Evidence map›Paper›PMID 29210028›Full record

ArticleAMB Express2017

Antimicrobial peptides sourced from post-butter processing waste yak milk protein hydrolysates.

Jinjin Pei, Hai Jiang, Xinsheng Li, Wengang Jin, Yanduo Tao

Open access · goldAbstract read
In one paragraph

Article in AMB Express, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
0.4field-weighted citation impact, top 35% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 23 citations in OpenAlex.

  1. Review
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  3. Polymorphisms within theFoods (Basel, Switzerland) · 2024
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Jinjin PeiShaanxi Key Laboratory of Biology and Bioresources, College of Bioscience and Bioengineering, Shaanxi University of Technology, Chaoyang Rd, Hanzhong, 723001, Shaanxi, China. jinjinpeislg@163.com.ORCID http://orcid.org/0000-0003-1301-3620
Hai JiangShaanxi Key Laboratory of Biology and Bioresources, College of Bioscience and Bioengineering, Shaanxi University of Technology, Chaoyang Rd, Hanzhong, 723001, Shaanxi, China.
Xinsheng LiShaanxi Key Laboratory of Biology and Bioresources, College of Bioscience and Bioengineering, Shaanxi University of Technology, Chaoyang Rd, Hanzhong, 723001, Shaanxi, China.
Wengang JinShaanxi Key Laboratory of Biology and Bioresources, College of Bioscience and Bioengineering, Shaanxi University of Technology, Chaoyang Rd, Hanzhong, 723001, Shaanxi, China.
Yanduo TaoKey Laboratory of Tibetan Medicine Research, Northwest Institute of Plateau Biology, Chinese Academy of Sciences Xining, Xining, 810081, China. tyd@nwipb.cas.cn.
Shaanxi University of Technology · CNChinese Academy of Sciences · CN

Funding

Collaborative innovation center Research Foundation QBXT-Z(P)-15-28Research Foundation of Science and Technology Bureau of Shaanxi, China 2015SZS-15-05Special Scientists' Foundations of Shaanxi University of Technology SLGKYQD2014-2-18the China Scholarship Council (CSC) Foundation 201608615024
6 · The paper itself

Abstract

Yak butter is one of the most important foods for the Tibetan people. Of note, its production yields waste yak milk as a by-product. In this work, waste yak milk protein hydrolysates made via Pepsin hydrolysis were shown to have antimicrobial activity. Furthermore, an innovative method of magnetic liposome adsorption combined with reversed-phase high performance liquid chromatography (RP-HPLC) was developed to screen for and purify the antimicrobial peptides. Two antimicrobial peptides were obtained and their amino acid sequences were determined by N-sequencing, namely Arg-Val-Met-Phe-Lys-Trp-Ala and Lys-Val-Ile-Ser-Met-Ile. The antimicrobial activity spectra of Arg-Val-Met-Phe-Lys-Trp-Ala included Bacillus subtilis, Staphylcoccus aureus, Listeria innocua, Escherichia coli, Enterobacter cloacae and Salmonella paratyphi, while the Lys-Val-Ile-Ser-Met-Ile peptide shows not only bacterial growth inhibition but also of fungi. Haemolytic testing suggested that these two antimicrobial peptides could be considered to have no haemolytic effect at their minimum inhibitory concentrations (MICs).

Indexed as

Antimicrobial peptidesHydrolysatesIsolationYak milk

Identifiers

PMID29210028
PMCPMC5716961
OpenAlexW2773456337

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.