Evidence map›Paper›PMID 29209923›Full record

ArticleMetabolic brain disease2018

Plasma microparticles in Alzheimer's disease: The role of vascular dysfunction.

Soheila Hosseinzadeh, Maryam Noroozian, Esmaeil Mortaz, Kazem Mousavizadeh

Abstract read
PubMed Publisher
In one paragraph

Article in Metabolic brain disease, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed.

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  12. Pollution, Particles, and Dementia: A Hypothetical Causative Pathway.International journal of environmental research and public health · 2020
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Soheila HosseinzadehNeuroscience Research Center, Health Research Institute, Babol University of Medical Sciences, Babol, Iran.
Maryam NoroozianMemory and Behavioral Neurology Division, Department of Psychiatry, Roozbeh Hospital, Tehran University of Medical Sciences, Tehran, 1333795914, Iran. maryam.noroozian.mn@gmail.com.
Esmaeil MortazDepartment of Immunology, National Research Institute of Tuberculosis and Lung Diseases (NRITLD), Shahid Beheshti University of Medical Sciences, Tehran, Iran.
Kazem MousavizadehCellular and Molecular Research Center and Department of Molecular Medicine, Faculty of Advanced Technologies in Medicine, Iran University of Medical Sciences, Tehran, Iran.

Funding

Research Affairs Division, Tehran University of Medical Sciences 16501
6 · The paper itself

Abstract

Cerebrovascular lesions, a potent stimulus for endothelial cell activation, trigger cognitive and degenerative changes and contribute to pathology of Alzheimer's disease (AD). Circulating microparticles (MPs) are actively involved in the pathogenesis of AD and cerebrovascular diseases, which share common vascular risk factors. We examined the plasma changes of endothelial MPs (EMPs) and platelet MPs (PMPs) in AD patients with vascular risk factors. The plasma Annexin V

Indexed as

AgedAged, 80 and overAlzheimer DiseaseCadherinsCell-Derived MicroparticlesEndothelial CellsEndothelium, VascularFemaleHumansMaleMiddle AgedRisk FactorsCadherinsAlzheimer’s diseaseBlood plateletsCell-derived microparticlesCognitive dysfunctionDementiaVascular risk factors

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.