Evidence map›Paper›PMID 29209868›Full record

ArticleLasers in medical science2018

Laser surface modification of decellularized extracellular cartilage matrix for cartilage tissue engineering.

Eva Goldberg-Bockhorn, Silke Schwarz, Rachana Subedi, Alexander Elsässer, Ricarda Riepl, Paul Walther, Ludwig Körber, Roman Breiter, Karl Stock, Nicole Rotter

Abstract read
PubMed Publisher
In one paragraph

Article in Lasers in medical science, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
1.5field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 18 citations in OpenAlex.

  1. Review
  2. Photobiomodulation in Promoting Cartilage Regeneration.International journal of molecular sciences · 2025
    Review
  3. Article
  4. Article
  5. Article
  6. Review
  7. Article
  8. Review
  9. Article
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 5 institutions in 1 country.

Eva Goldberg-BockhornDepartment of Otorhinolaryngology, Head and Neck Surgery, Ulm University Medical Center, Frauensteige 12, 89075, Ulm, Germany. eva.goldberg@uniklinik-ulm.de.
Silke SchwarzDepartment of Anatomy, Paracelsus Medical University, Salzburg and Nuernberg, Prof. Ernst Nathan Str. 1, 90419, Nuernberg, Germany.
Rachana SubediDepartment of Otorhinolaryngology, Head and Neck Surgery, Ulm University Medical Center, Frauensteige 12, 89075, Ulm, Germany.
Alexander ElsässerDepartment of Otorhinolaryngology, Head and Neck Surgery, Ulm University Medical Center, Frauensteige 12, 89075, Ulm, Germany.
Ricarda RieplDepartment of Otorhinolaryngology, Head and Neck Surgery, Ulm University Medical Center, Frauensteige 12, 89075, Ulm, Germany.
Paul WaltherCentral Facility for Electron Microscopy, Ulm University, Albert-Einstein-Allee 11, 89081, Ulm, Germany.
Ludwig KörberInstitute of Bioprocess Engineering, Erlangen University, Paul-Gordan-Str. 3, 91052, Erlangen, Germany.
Roman BreiterChair of Medical Bio-Technology, University of Erlangen, Paul-Gordan-Str. 3, 91052, Erlangen, Germany.
Karl StockInstitut für Lasertechnologien in der Medizin und Meßtechnik, an der Universität Ulm, Helmholtzstr. 12, 89081, Ulm, Germany.
Nicole RotterDepartment of Otorhinolaryngology, Mannheim University Medical Center, Theodor-Kutzer-Ufer 1-3, 68167, Mannheim, Germany.
Universität Ulm · DEFriedrich-Alexander-Universität Erlangen-Nürnberg · DEInstitute for Laser Technology in Medicine and Measurement Technique · DEParacelsus Medizinische Privatuniversität · DEUniversity Medical Centre Mannheim · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The implantation of autologous cartilage as the gold standard operative procedure for the reconstruction of cartilage defects in the head and neck region unfortunately implicates a variety of negative effects at the donor site. Tissue-engineered cartilage appears to be a promising alternative. However, due to the complex requirements, the optimal material is yet to be determined. As demonstrated previously, decellularized porcine cartilage (DECM) might be a good option to engineer vital cartilage. As the dense structure of DECM limits cellular infiltration, we investigated surface modifications of the scaffolds by carbon dioxide (CO

Indexed as

Lasers, SemiconductorAdultAggrecansAnimalsCartilageCell DeathCell MovementCells, CulturedChondrocytesCollagen Type IIExtracellular MatrixHumansSurface PropertiesSus scrofaTissue EngineeringTissue ScaffoldsAggrecansCollagen Type IICarbon dioxide laserCartilageChondrocytesEr:YAG laserSurface modificationTissue engineering

Identifiers

PMID29209868
OpenAlexW2772876594

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.