Evidence map›Paper›PMID 29209851›Full record

ReviewEuropean archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery2018

Elevated parathyroid hormone levels after successful parathyroidectomy for primary hyperparathyroidism: a clinical review.

Roberto de la Plaza Llamas, José Manuel Ramia Ángel, Vladimir Arteaga Peralta, Cristina García Amador, Aylhín Joana López Marcano, Aníbal Armando Medina Velasco, Begoña González Sierra, Alba Manuel Vázquez, Raquel Aránzazu Latorre Fragua

Abstract readReview
PubMed Publisher
In one paragraph

Review in European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
1.3field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 40 citations in OpenAlex.

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  16. [Normocalcemic with elevated post-operative parathormone in primary hyperpara-thyroidism: 9 case reports and literature review].Beijing da xue xue bao. Yi xue ban = Journal of Peking University. Health sciences · 2021
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

Roberto de la Plaza LlamasDepartment of Surgery, Hospital General Universitario de Guadalajara, C/ Calle del Donante de sangre s/n, 19002, Guadalajara, Spain. rdplazal@sescam.jccm.es.ORCID http://orcid.org/0000-0001-9501-5480
José Manuel Ramia ÁngelDepartment of Surgery, Hospital General Universitario de Guadalajara, C/ Calle del Donante de sangre s/n, 19002, Guadalajara, Spain.
Vladimir Arteaga PeraltaDepartment of Surgery, Hospital General Universitario de Guadalajara, C/ Calle del Donante de sangre s/n, 19002, Guadalajara, Spain.
Cristina García AmadorDepartment of Surgery, Hospital General Universitario de Guadalajara, C/ Calle del Donante de sangre s/n, 19002, Guadalajara, Spain.
Aylhín Joana López MarcanoDepartment of Surgery, Hospital General Universitario de Guadalajara, C/ Calle del Donante de sangre s/n, 19002, Guadalajara, Spain.
Aníbal Armando Medina VelascoDepartment of Surgery, Hospital General Universitario de Guadalajara, C/ Calle del Donante de sangre s/n, 19002, Guadalajara, Spain.
Begoña González SierraDepartment of Surgery, Hospital General Universitario de Guadalajara, C/ Calle del Donante de sangre s/n, 19002, Guadalajara, Spain.
Alba Manuel VázquezDepartment of Surgery, Hospital General Universitario de Guadalajara, C/ Calle del Donante de sangre s/n, 19002, Guadalajara, Spain.
Raquel Aránzazu Latorre FraguaDepartment of Surgery, Hospital General Universitario de Guadalajara, C/ Calle del Donante de sangre s/n, 19002, Guadalajara, Spain.
Hospital Universitario de Guadalajara · ES

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionSurgery for primary hyperparathyroidism (PHPT) is traditionally deemed to be successful if serum calcium levels return to normal 6 months after parathyroidectomy. Regular monitoring of serum calcium and parathyroid hormone (PTH) in the follow-up of patients after parathyroidectomy for PHPT has drawn attention to the presence of a normocalcemic group of patients with elevated PTH (NCePTH) during the post-operative period. The etiological factors and mechanisms underlying this condition, its consequences, and the possibility of treatment are the object of this study. MATERIALS AND

methodsWe conducted an unlimited PubMed search updated on March 31, 2017, which yielded 1628 results. We selected 37 articles, 33 of which included cases of NCePTH in their series and 23 performed statistical studies to assess factors associated with NCePTH.

resultsThe maximum mean prevalence of NCePTH in the various series was 23.5%, ranging from 3 to 46%. Many factors were associated with NCePTH. The most important were higher pre-operative PTH, low pre-operative 25 (OH) D3, lower pre-operative creatinine clearance and greater adenoma weight. The origin of NCePTH may be multifactorial, since several factors were implicated in the etiology. NCePTH does not seem to be related to an increase in PHPT recurrence, although this possibility should not be dismissed. Vitamin D deficiency should be corrected. Treatment with calcium supplements seems to be clearly beneficial.

conclusionThe prevalence of NCePTH is high. The causes of secondary hyperparathyroidism should be investigated carefully. Patients require treatment and long-term follow-up.

Indexed as

ParathyroidectomyAdenomaCalcifediolCalciumHumansHyperparathyroidism, PrimaryNeoplasm Recurrence, LocalParathyroid HormoneParathyroid NeoplasmsPostoperative ComplicationsVitamin D DeficiencyCalcifediolCalciumParathyroid HormoneHyperparathyroidism, PrimaryParathyroidectomyParathyroid hormonePost-operative hyperparathyroidismPost-operative periodReview

Identifiers

PMID29209851
OpenAlexW2771340254

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.