Evidence map›Paper›PMID 29209792›Full record

ArticleRheumatology international2018

The impact of smoking on disease measures in rheumatoid arthritis: the need for appropriate adjustment of time-varying confounding.

Milena A Gianfrancesco, Jinoos Yazdany, Gabriela Schmajuk

Abstract readLetterComment
In one paragraph

Article in Rheumatology international, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact, top 73% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 1 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Milena A GianfrancescoDivision of Rheumatology, Department of Medicine, University of California, 513 Parnassus Avenue, San Francisco, CA, 94143, USA. milena.gianfrancesco@ucsf.edu.ORCID 0000-0002-8351-4626
Jinoos YazdanyDivision of Rheumatology, Department of Medicine, University of California, 513 Parnassus Avenue, San Francisco, CA, 94143, USA.
Gabriela SchmajukDivision of Rheumatology, Department of Medicine, University of California, 513 Parnassus Avenue, San Francisco, CA, 94143, USA.
University of California, San Francisco · USSan Francisco VA Medical Center · US

Funding

RESOURCE-BASED CENTER FOR THE ADVANCEMENT OF PRECISION MEDICINE IN RHEUMATOLOGYP30AR070155 · NIAMS · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI Mary C Nakamura · 2016 to 2026
$8.2M
ASPIRE: Advancing Safety Process Innovation in RheumatologyR01HS024412 · AHRQ · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI YAZDANY, JINOOS · 2015 to 2017
$1.4M
A rational approach to liver toxicity monitoring in methotrexate usersK23AR063770 · NIAMS · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI SCHMAJUK, GABRIELA · 2013 to 2017
$670k
Examining the causal effect of sociodemographic and genetic factors on patient safety outcomes in individuals prescribed high-risk immunosuppressive medicationsF32AR070585 · NIAMS · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI GIANFRANCESCO, MILENA ANNE · 2017 to 2018
$125k
AHRQ HHS R01 HS024412NIAMS NIH HHS F32 AR070585NIAMS NIH HHS K23 AR063770NIAMS NIH HHS P30 AR070155
6 · The paper itself

Abstract

In a recent publication, Quintana-Dunque et al. studied patients with early onset rheumatoid arthritis (RA) and showed that baseline smoking status was inversely associated with disease activity and disability at 36 months. The authors conclude that smoking may not be as deleterious as previously considered in RA disease course. However, the authors fail to highlight several limitations of study design and analysis, including time-varying confounding, which may have a direct impact on results and corresponding conclusions.

Indexed as

Arthritis, RheumatoidSmokingDisease ProgressionHumansPersons with DisabilitiesResearch Design

Identifiers

PMID29209792
PMCPMC5775037
OpenAlexW2774333488

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.