Evidence map›Paper›PMID 29209743›Full record

ArticleNaunyn-Schmiedeberg's archives of pharmacology2018

Gastroprotective activity of the methanol extract from peels of Plinia edulis (Vell.) Sobral fruits and its isolated triterpenes: maslinic and ursolic acids.

Roseane Leandra da Rosa, Luciane Ângela Nottar Nesello, Luisa Nathalia Bolda Mariano, Lincon Bordignon Somensi, Adriana Campos, Ana Myrelle Pinheiro, Sabrina Costa, Marjana Rial, Mariana Tozzo, Valdir Cechinel-Filho and 2 more

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In one paragraph

Article in Naunyn-Schmiedeberg's archives of pharmacology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
0.6field-weighted citation impact, top 33% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 17 citations in OpenAlex.

  1. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 1 institution in 1 country.

Roseane Leandra da RosaPrograma de Pós-Graduação em Ciências Farmacêuticas, Universidade do Vale do Itajai (UNIVALI), Campus Itajai, Rua Uruguai, 458, Centro, Santa Catarina, 88302-901, Brazil.
Luciane Ângela Nottar NeselloPrograma de Pós-Graduação em Ciências Farmacêuticas, Universidade do Vale do Itajai (UNIVALI), Campus Itajai, Rua Uruguai, 458, Centro, Santa Catarina, 88302-901, Brazil.
Luisa Nathalia Bolda MarianoPrograma de Pós-Graduação em Ciências Farmacêuticas, Universidade do Vale do Itajai (UNIVALI), Campus Itajai, Rua Uruguai, 458, Centro, Santa Catarina, 88302-901, Brazil.
Lincon Bordignon SomensiPrograma de Pós-Graduação em Ciências Farmacêuticas, Universidade do Vale do Itajai (UNIVALI), Campus Itajai, Rua Uruguai, 458, Centro, Santa Catarina, 88302-901, Brazil.
Adriana CamposPrograma de Pós-Graduação em Ciências Farmacêuticas, Universidade do Vale do Itajai (UNIVALI), Campus Itajai, Rua Uruguai, 458, Centro, Santa Catarina, 88302-901, Brazil.
Ana Myrelle PinheiroCurso de Nutrição, UNIVALI, Campus Itajai, Rua Uruguai, 458, Centro, Santa Catarina, 88302-901, Brazil.
Sabrina CostaCurso de Nutrição, UNIVALI, Campus Itajai, Rua Uruguai, 458, Centro, Santa Catarina, 88302-901, Brazil.
Marjana RialCurso de Biomedicina, UNIVALI, Campus Itajai, Rua Uruguai, 458, Centro, Santa Catarina, 88302-901, Brazil.
Mariana TozzoCurso de Biomedicina, UNIVALI, Campus Itajai, Rua Uruguai, 458, Centro, Santa Catarina, 88302-901, Brazil.
Valdir Cechinel-FilhoPrograma de Pós-Graduação em Ciências Farmacêuticas, Universidade do Vale do Itajai (UNIVALI), Campus Itajai, Rua Uruguai, 458, Centro, Santa Catarina, 88302-901, Brazil.
Sérgio Faloni de AndradePrograma de Pós-Graduação em Ciências Farmacêuticas, Universidade do Vale do Itajai (UNIVALI), Campus Itajai, Rua Uruguai, 458, Centro, Santa Catarina, 88302-901, Brazil.
Luísa Mota Da SilvaPrograma de Pós-Graduação em Ciências Farmacêuticas, Universidade do Vale do Itajai (UNIVALI), Campus Itajai, Rua Uruguai, 458, Centro, Santa Catarina, 88302-901, Brazil. lu.isamota@hotmail.com.
Universidade do Vale do Itajaí · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

According to the Brazilian folk medicine, the leaves of Plinia edulis (Vell.) Sobral (Myrtaceae), known as cambuca, are indicated in the treatment of gastric disorders. Infusions of P. edulis leaves were previously demonstrated to contain both maslinic (MA) and ursolic acids (UA). Both triterpenes have also been identified in the methanolic extract of peels from P. edulis fruit (MEPPE); however, the antiulcer effects of MEPPE have not yet been studied. This study therefore evaluates the gastroprotective potential of MEPPE, MA, and UA using ethanol/HCl- and indomethacin-induced gastric ulcers in mice. In addition, the in vitro effects of these compounds on the H

Indexed as

FruitMyrtaceaeAnimalsAnti-Ulcer AgentsDose-Response Relationship, DrugFemaleMethanolMiceOleanolic AcidPlant ExtractsStomach UlcerTriterpenesUrsolic AcidAnti-Ulcer Agentsmaslinic acidMethanolOleanolic AcidPlant ExtractsTriterpenesUrsolic AcidAntiulcerFruitsGastric ulcerH+, K+-ATPaseTriterpene

Identifiers

PMID29209743
OpenAlexW2772628745

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.