ArticleEFORT open reviews2017
Diagnosis and treatment of soft-tissue sarcomas of the extremities and trunk.
Article in EFORT open reviews, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 33 papers, 1 of them a synthesis that pooled it.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
33 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Follow-up Strategies for Primary Extremity Soft-tissue Sarcoma in Adults: A Systematic Review of the Published Literature.In vivo (Athens, Greece)Pooled it
- Predicting pathological complete response of neoadjuvant radiotherapy and targeted therapy for soft tissue sarcoma by whole-tumor texture analysis of multisequence MRI imaging.European radiology · 2023Trial
- Deep-learning-aided sarcoma biopsy guidance using forward-view endoscopic optical coherence tomography.Biomedical optics express · 2026Article
- What are the surgical and oncologic outcomes, as well as the complications, associated with pre-operative radiotherapy in patients with low-grade soft-tissue sarcoma?International journal of clinical oncology · 2026Article
- Infectious complications and outcomes after limb salvage surgery with vascular reconstruction: A retrospective analysis from a lower middle-income country.Pakistan journal of medical sciences · 2026Article
- Multiparametric assessment of high-grade pediatric soft-tissue sarcomas with anatomic and functional MRI sequences: a retrospective study.Skeletal radiology · 2026Article
- Neuromotor Compromise as a Presenting Symptom in Advanced Lower Extremity Soft Tissue Sarcoma: A Case Series.HCA healthcare journal of medicine · 2026Article
- Soft tissue hematomas on ultrasound: a case-based review and practical guide to diagnosis.Journal of ultrasonography · 2025Review
- Reconstructive Arthroplasty for Malignant Bone Tumors of the Knee-A Single-Center Experience of Functionality and Quality of Life.Journal of clinical medicine · 2025Article
- Histological Grade, Tumor Breadth, and Hypertension Predict Early Recurrence in Pediatric Sarcoma: A LASSO-Regularized Micro-Cohort Study.Children (Basel, Switzerland) · 2025Article
- Diagnostic work-up of lipomatous tumors: a decision-making analysis among European sarcoma centers.Insights into imaging · 2025Article
- Rethinking the Prognostic Role of Necrosis in Soft-Tissue Sarcoma: Multidisciplinary Insights from the Sarcoma Academy.Cancers · 2025Article
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- The Effect of chemo- and radiotherapy on tumor necrosis in soft tissue sarcoma- does it influence prognosis?BMC cancer · 2024Article
- Do Patients Treated With an Unplanned Resection for Small Superficial Soft Tissue Sarcomas Have Worse Long-term Survival Than Those Initially Treated With an Oncologic Resection?Clinical orthopaedics and related research · 2024Article
- Chronic Lower Limb Pain Unveiling a Rare Case of Spindle Cell Soft Tissue Sarcoma: A Diagnostic Odyssey.Cureus · 2023Article
- Patients' Experiences of a Sarcoma Diagnosis: A Process Mapping Exercise of Diagnostic Pathways.Cancers · 2023Article
- Epidemiology and survival factors of appendicular myxofibrosarcoma: a SEER-retrospective study.Reports of practical oncology and radiotherapy : journal of Greatpoland Cancer Center in Poznan and Polish Society of Radiation Oncology · 2023Article
- Sarcomas of the extremities and the pelvis: comparing local recurrence after incisional and after core-needle biopsy.World journal of surgical oncology · 2022Article
Corrections and comments
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Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The relatively low incidence and often atypical clinical presentation of soft-tissue sarcomas (STS) impedes early and adequate diagnosis. Patients may report on recently enlarged soft-tissue swellings, infrequently complain of painful lesions, or even have no symptoms at all.A thorough diagnostic work-up is essential in order to distinguish between benign soft-tissue tumours and STSs. Patient history, clinical features and radiological findings all help in assessing the underlying pathology. 'Worrying' features such as recent increase in size, deep location relative to the fascia, a tumour exceeding 4 cm in size, and invasive growth patterns seen on imaging should prompt verification by biopsy.Even though acquisition of biopsy material may be incomplete, one should bear in mind some essential rules. Regardless of the biopsy technique applied, the most direct route to the lump in question should be identified, contamination of adjacent structures should be avoided and a sufficient amount of tissue acquired.Treatment of STS is best planned by a multidisciplinary team, involving experts from various medical specialities. The benchmark therapy consists of
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