ArticleFrontiers in plant science2017
Regulation of Fig (
Article in Frontiers in plant science, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 114 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
114 citing papers in PubMed, 265 citations in OpenAlex.
- Widely Targeted Metabolomics Reveals Metabolic Differences Between Yellow and Brown Flaxseed Cultivars (Foods (Basel, Switzerland) · 2026Article
- A high-quality chromosome-level genome assembly of Ficus carica cultivar 'Green Peel'.Scientific data · 2026Article
- Investigating phenolic compounds, antioxidant activity, and pomological traits in highbush blueberry (Vaccinium corymbosum L.) cultivars across ripening stages.BMC plant biology · 2026Article
- Transcriptomic and Metabolomic Insights into the Enhanced Quality ofMetabolites · 2026Article
- Phenolic Copigment Enhanced Anthocyanin Stability and Color Intensity of Frozen Red Huajiao (Foods (Basel, Switzerland) · 2026Article
- Identification and Validation of Reference Genes for Quantitative Real-Time PCR inPlants (Basel, Switzerland) · 2025Article
- Genome-Wide Analysis of the Common Fig (Ficus carica L.) R2R3-MYB Genes Reveals Their Structure, Evolution, and Roles in Fruit Color Variation.Biochemical genetics · 2025Article
- Combined analysis of the metabolome and transcriptome reveals the mechanism of Red heart Chinese fir heartwood formation.Scientific reports · 2025Article
- Carotenoid metabolomic and transcriptomic analyses provide insights into the flower color transition in Lonicera macranthoides.BMC biotechnology · 2025Article
- Metabolic Pathways and Molecular Regulatory Mechanisms of Fruit Color Change During Greening Stage of Peppers (International journal of molecular sciences · 2025Article
- Genome-wide identification, characterization and expression analysis of WRKY transcription factors under abiotic stresses in Carthamus tinctorius L.BMC plant biology · 2025Article
- Integrated transcriptomics and metabolomics analysis of flower petals color transition in different phenotype ofFrontiers in plant science · 2025Article
- Metabolomics Combined with Transcriptomics Analysis Reveals the Regulation of Flavonoids in the Leaf Color Change ofInternational journal of molecular sciences · 2024Article
- Genome-Wide Identification of the bHLH Gene Family inInternational journal of molecular sciences · 2024Article
- Analysis of the Mechanism of Wood Vinegar and Butyrolactone Promoting Rapeseed Growth and Improving Low-Temperature Stress Resistance Based on Transcriptome and Metabolomics.International journal of molecular sciences · 2024Article
- Modifications in gene expression and phenolic compounds content by methyl jasmonate and fungal elicitors in Ficus carica. Cv. Siah hairy root cultures.BMC plant biology · 2024Article
- Integrated transcriptome and metabolome analysis reveals the regulation of phlorizin synthesis in Lithocarpus polystachyus under nitrogen fertilization.BMC plant biology · 2024Article
- Transcriptomic and targeted metabolomic analyses provide insights into the flavonoids biosynthesis in the flowers of Lonicera macranthoides.BMC biotechnology · 2024Article
- Comparative transcriptome and metabolome profiles of the leaf and fruits of a Xianjinfeng litchi budding mutant and its mother plant.Frontiers in genetics · 2024Article
- Fine genetic mapping and transcriptomic analysis revealed major gene modulating the clear stripe margin pattern of watermelon peel.Frontiers in plant science · 2024Article
54 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Combined metabolomic and transcriptomic analyses were carried out with fig cultivar Green Peel and its color mutant "Purple Peel." Five and twenty-two metabolites were identified as having significantly different contents between fruit peels of the two cultivars at young and mature stages, respectively. Cyanidin O-malonylhexoside demonstrated a 3,992-fold increase in the mature purple peel, the first identification of a major cyanidin in fig fruit; cyanidin 3-O-glucoside, cyanidin O-malonylhexoside O-hexoside and cyanidin-3,5-O-diglucoside were upregulated 100-fold, revealing the anthocyanins underlying the purple mutation. Beyond the visible differences, there was very significant accumulation of the colorless flavonoids procyanidin B1, luteolin-3',7-di-O-glucoside, epicatechin and quercetin-3-O-rhamnoside in the mature "Purple Peel" compared to "Green Peel." At the young stage, only cyanidin O-malonylhexoside, cyanidin O-malonylhexoside O-hexoside and esculetin were upregulated a few fold in the mutant. Transcriptome analysis revealed a downregulated expression trend of genes encoding phenylpropanoid and flavonoid biosynthetic pathway enzyme in the young "Purple Peel" compared to the young "Green Peel," whereas significant and simultaneous upregulation was revealed in almost all of the flavonoid and anthocyanin pathway components and relevant transcription factors in the mature-stage mutant. The role of R2R3-MYB transcription factors in the color morph mutation and its possible relation to the activity of retrotransposons are discussed. Moreover, large-scale upregulation of small heat-shock protein genes was found in the mature mutant. This is the first work to reveal comprehensive metabolome and transcriptome network changes underlying a fig mutation in a single horticultural attribute, and its profound effects on fruit nutrition and quality.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.