ReviewFrontiers in microbiology2017
Revisiting Antibiotic Resistance Spreading in Wastewater Treatment Plants - Bacteriophages as a Much Neglected Potential Transmission Vehicle.
Review in Frontiers in microbiology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 42 papers.
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Who cites it
42 citing papers in PubMed.
- Bacteriophage survival and ARG dissemination from wastewater treatment plants to the environment.Applied microbiology and biotechnology · 2026Review
- Exploring the host-pathogen interaction and genome analysis of multidrug-resistant bacterial pathogenFrontiers in immunology · 2026Article
- Article
- Multidrug-resistant E. Coli in wastewater sources: a comparative study and identification of resistance hotspots.BMC microbiology · 2025Article
- Illuminating the Invisible: Green Fluorescent Protein as a Beacon for Antibiotic-Induced Phage Activity inAntibiotics (Basel, Switzerland) · 2025Article
- Evolution of Antiviral Drug Resistance in SARS-CoV-2.Viruses · 2025Review
- Molecular characterization and virulence of fungal pathogens associated with mass mortalities in hilsa Shad (Tenualosa ilisha).Scientific reports · 2025Article
- Article
- The dual nature of plant growth-promoting bacteria: Benefits, risks, and pathways to sustainable deployment.Current research in microbial sciences · 2025Review
- Review
- Article
- A Review of the Dissemination of Antibiotic Resistance through Wastewater Treatment Plants: Current Situation in Sri Lanka and Future Perspectives.Life (Basel, Switzerland) · 2024Review
- Temperature-Driven Activated Sludge Bacterial Community Assembly and Carbon Transformation Potential: A Case Study of Industrial Plants in the Yangtze River Delta.Microorganisms · 2024Article
- Distribution of bacterial community structures and spread of antibiotic resistome at industrially polluted sites of Mini River, Vadodara, Gujarat, India.Environmental monitoring and assessment · 2024Article
- Deciphering the impact of endoparasitic infection on immune response and gut microbial composition ofFrontiers in cellular and infection microbiology · 2024Article
- An Eco-evolutionary Model on Surviving Lysogeny Through Grounding and Accumulation of Prophages.Microbial ecology · 2023Article
- Unveiling Rare Pathogens and Antibiotic Resistance in Tanzanian Cholera Outbreak Waters.Microorganisms · 2023Article
- Biogeographical variation in antimicrobial resistance in rivers is influenced by agriculture and is spread through bacteriophages.Environmental microbiology · 2022Article
- Article
- Enrichment of antibiotic resistance genes within bacteriophage populations in saliva samples from individuals undergoing oral antibiotic treatments.Frontiers in microbiology · 2022Article
Corrections and comments
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Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The spread of antibiotic resistance is currently a major threat to health that humanity is facing today. Novel multidrug and pandrug resistant bacteria are reported on a yearly basis, while the development of novel antibiotics is lacking. Focus to limit the spread of antibiotic resistance by reducing the usage of antibiotics in health care, veterinary applications, and meat production, have been implemented, limiting the exposure of pathogens to antibiotics, thus lowering the selection of resistant strains. Despite these attempts, the global resistance has increased significantly. A recent area of focus has been to limit the spread of resistance through wastewater treatment plants (WWTPs), serving as huge reservoirs of microbes and resistance genes. While being able to quite efficiently reduce the presence of resistant bacteria entering any of the final products of WWTPs (e.g., effluent water and sludge), the presence of resistance genes in other formats (mobile genetic elements, bacteriophages) has mainly been ignored. Recent data stress the importance of transduction in WWTPs as a mediator of resistance spread. Here we examine the current literature in the role of WWTPs as reservoirs and hotspots of antibiotic resistance with a specific focus on bacteriophages as mediators of genetic exchange.
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