Evidence map›Paper›PMID 29209301›Full record

ArticleFrontiers in microbiology2017

The Antifungal Plant Defensin HsAFP1 Is a Phosphatidic Acid-Interacting Peptide Inducing Membrane Permeabilization.

Tanne L Cools, Kim Vriens, Caroline Struyfs, Sara Verbandt, Marcelo H S Ramada, Guilherme D Brand, Carlos Bloch, Barbara Koch, Ana Traven, Jan W Drijfhout and 7 more

Abstract read
In one paragraph

Article in Frontiers in microbiology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers.

0numbers the graph read from it
0cells of the map it votes in
29citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

29 citing papers in PubMed.

  1. Article
  2. Antifungal Peptides SmAPAntibiotics (Basel, Switzerland) · 2025
    Article
  3. Review
  4. Review
  5. Article
  6. Review
  7. Article
  8. Article
  9. Antimicrobial Peptides with Anti-International journal of molecular sciences · 2022
    Review
  10. Review
  11. Review
  12. Article
  13. Article
  14. Fungicidal Activity of Recombinant Javanicin againstMolecules (Basel, Switzerland) · 2021
    Article
  15. Article
  16. Membrane-Interacting Antifungal Peptides.Frontiers in cell and developmental biology · 2021
    Review
  17. Article
  18. Modulation of Lymphocyte Potassium Channel KACS pharmacology & translational science · 2020
    Article
  19. Article
  20. Plant Defensins from a Structural Perspective.International journal of molecular sciences · 2020
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors.

Tanne L CoolsCentre of Microbial and Plant Genetics, KU Leuven, Leuven, Belgium.
Kim VriensCentre of Microbial and Plant Genetics, KU Leuven, Leuven, Belgium.
Caroline StruyfsCentre of Microbial and Plant Genetics, KU Leuven, Leuven, Belgium.
Sara VerbandtCentre of Microbial and Plant Genetics, KU Leuven, Leuven, Belgium.
Marcelo H S RamadaGraduate Program in Genomic Sciences and Biotechnology, Catholic University of Brasilia, Brasilia, Brazil.
Guilherme D BrandChemistry Institute, Campus Darcy Ribeiro, University of Brasilia, Brasilia, Brazil.
Carlos BlochMass Spectrometry Laboratory, Embrapa Genetic Resources and Biotechnology, Brasilia, Brazil.
Barbara KochDepartment of Biochemistry and Molecular Biology, Monash University, Clayton, VIC, Australia.
Ana TravenDepartment of Biochemistry and Molecular Biology, Monash University, Clayton, VIC, Australia.
Jan W DrijfhoutDepartment of Immunohematology and Blood Transfusion, Leiden University Medical Center, Leiden, Netherlands.
Liesbeth DemuyserLaboratory of Molecular Cell Biology, KU Leuven, Leuven, Belgium.
Soňa KucharíkováLaboratory of Molecular Cell Biology, KU Leuven, Leuven, Belgium.
Patrick Van DijckLaboratory of Molecular Cell Biology, KU Leuven, Leuven, Belgium.
Dragana SpasicBIOSYST-MeBioS, KU Leuven, Leuven, Belgium.
Jeroen LammertynBIOSYST-MeBioS, KU Leuven, Leuven, Belgium.
Bruno P A CammueCentre of Microbial and Plant Genetics, KU Leuven, Leuven, Belgium.
Karin ThevissenCentre of Microbial and Plant Genetics, KU Leuven, Leuven, Belgium.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

HsAFP1, a plant defensin isolated from coral bells (

Indexed as

antifungal mode of actionlipid membrane targetmembrane permeabilizationpeptide internalizationplant defensinsyeast

Identifiers

PMID29209301
PMCPMC5702387

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.