Evidence map›Paper›PMID 29209201›Full record

ArticleFrontiers in aging neuroscience2017

Do Lifestyle Activities Protect Against Cognitive Decline in Aging? A Review.

Gregory J Christie, Tara Hamilton, Bradley D Manor, Norman A S Farb, Faranak Farzan, Andrew Sixsmith, Jean-Jacques Temprado, Sylvain Moreno

Abstract read
In one paragraph

Article in Frontiers in aging neuroscience, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 34 papers.

0numbers the graph read from it
0cells of the map it votes in
34citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

34 citing papers in PubMed.

  1. Trial
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  4. Interpretable machine learning for precision cognitive aging.Frontiers in computational neuroscience · 2025
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  14. Out-of-Home Activities and Health in Older Adults: A Scoping Review.OTJR : occupation, participation and health · 2021
    Article
  15. Article
  16. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Gregory J ChristieDigital Health Hub, Simon Fraser University, Surrey, BC, Canada.
Tara HamiltonDigital Health Hub, Simon Fraser University, Surrey, BC, Canada.
Bradley D ManorInstitute for Aging Research, Harvard Medical School, Boston, MA, United States.
Norman A S FarbDepartment of Psychology, University of Toronto, Mississauga, ON, Canada.
Faranak FarzanDigital Health Hub, Simon Fraser University, Surrey, BC, Canada.
Andrew SixsmithDigital Health Hub, Simon Fraser University, Surrey, BC, Canada.
Jean-Jacques TempradoInstitut des Sciences du Mouvement, Faculté des Sciences du Sport, Aix-Marseille Université, Marseille, France.
Sylvain MorenoDigital Health Hub, Simon Fraser University, Surrey, BC, Canada.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The number of patients suffering from dementia is expected to more than triple by the year 2040, and this represents a major challenge to publicly-funded healthcare systems throughout the world. One of the most effective prevention mechanisms against dementia lies in increasing brain- and cognitive-reserve capacity, which has been found to reduce the behavioral severity of dementia symptoms as neurological degeneration progresses. To date though, most of the factors known to enhance this reserve stem from largely immutable history factors, such as level of education and occupational attainment. Here, we review the potential for basic lifestyle activities, including physical exercise, meditation and musical experience, to contribute to reserve capacity and thus reduce the incidence of dementia in older adults. Relative to other therapies, these activities are low cost, are easily scalable and can be brought to market quickly and easily. Overall, although preliminary evidence is promising at the level of randomized control trials, the state of research on this topic remains underdeveloped. As a result, several important questions remain unanswered, including the amount of training required to receive any cognitive benefit from these activities and the extent to which this benefit continues following cessation. Future research directions are discussed for each lifestyle activity, as well as the potential for these and other lifestyle activities to serve as both a prophylactic and a therapeutic treatment for dementia.

Indexed as

agingcognitive healthdementialifestyle factorsneuroplasticity

Identifiers

PMID29209201
PMCPMC5701915

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.