Evidence map›Paper›PMID 29209165›Full record

ArticleFrontiers in molecular neuroscience2017

MicroRNA-133b Negatively Regulates Zebrafish Single Mauthner-Cell Axon Regeneration through Targeting

Rongchen Huang, Min Chen, Leiqing Yang, Mahendra Wagle, Su Guo, Bing Hu

Open access · goldAbstract read
In one paragraph

Article in Frontiers in molecular neuroscience, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed
0.8field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed, 32 citations in OpenAlex.

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  17. Visualizing the Intracellular Trafficking in Zebrafish Mauthner Cells.Methods in molecular biology (Clifton, N.J.) · 2022
    Article
  18. Article
  19. The microtubule regulatorGenes & development · 2020
    Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 2 countries.

Rongchen HuangChinese Academy of Sciences Key Laboratory of Brain Function and Disease, School of Life Sciences, University of Science and Technology of China, Hefei, China.
Min ChenChinese Academy of Sciences Key Laboratory of Brain Function and Disease, School of Life Sciences, University of Science and Technology of China, Hefei, China.
Leiqing YangChinese Academy of Sciences Key Laboratory of Brain Function and Disease, School of Life Sciences, University of Science and Technology of China, Hefei, China.
Mahendra WaglePrograms in Human Genetics and Biological Sciences, Department of Bioengineering and Therapeutic Sciences, University of California, San Francisco, San Francisco, CA, United States.
Su GuoPrograms in Human Genetics and Biological Sciences, Department of Bioengineering and Therapeutic Sciences, University of California, San Francisco, San Francisco, CA, United States.
Bing HuChinese Academy of Sciences Key Laboratory of Brain Function and Disease, School of Life Sciences, University of Science and Technology of China, Hefei, China.
Chinese Academy of Sciences · CNUniversity of California, San Francisco · USUniversity of Science and Technology of China · CN

Funding

Asymmetric Cell Division in Vertebrate Brain DevelopmentR01NS095734 · NINDS · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI GUO, SU · 2015 to 2019
$1.7M
Developing tools for understanding neuromodulation of hypothalamic funcR01DA035680 · NIDA · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI GUO, SU · 2013 to 2017
$1.7M
NIDA NIH HHS R01 DA035680NINDS NIH HHS R01 NS095734
6 · The paper itself

Abstract

Axon regeneration, fundamental to nerve repair, and functional recovery, relies on rapid changes in gene expression attributable to microRNA (miRNA) regulation. MiR-133b has been proved to play an important role in different organ regeneration in zebrafish, but its role in regulating axon regeneration

Indexed as

axon regenerationin vivo imagingmiR-133bsingle-cell electroporationsingle-cell leveltppp3

Identifiers

PMID29209165
PMCPMC5702462
OpenAlexW2770070558

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.