ArticleFrontiers in neuroscience2017
Characterization of Cochlear, Vestibular and Cochlear-Vestibular Electrically Evoked Compound Action Potentials in Patients with a Vestibulo-Cochlear Implant.
Article in Frontiers in neuroscience, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 4 registered trials, which are not on this map. Cited by 10 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
VertiGO! - Get up and GO! With the Vestibular Implant
Tonotopische Cochlea-Stimulation Und Der Einfluss Auf Das Vestibularorgan
Electrical Stimulation of the Peripheral Vestibular System in Order to Develop a Vestibular Implant
Vestibular Implant Tested in Patients With Peripheral Vestibular Damage: Effects on Spatial Orientation, Navigation, and Neuropsychologic Function
Who cites it
10 citing papers in PubMed, 20 citations in OpenAlex.
- Optimizing vestibular implant electrode positioning using fluoroscopy and intraoperative CT imaging.European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 2024Article
- The vestibular implant: effects of stimulation parameters on the electrically-evoked vestibulo-ocular reflex.Frontiers in neurology · 2024Article
- Article
- Vestibular prosthesis: from basic research to clinics.Frontiers in integrative neuroscience · 2023Review
- Etiologies and hearing status in bilateral vestibulopathy: a retrospective study of 315 patients.Frontiers in neurology · 2023Article
- Computer Simulation of the Electrical Stimulation of the Human Vestibular System: Effects of the Reactive Component of Impedance on Voltage Waveform and Nerve Selectivity.Journal of the Association for Research in Otolaryngology : JARO · 2022Article
- CYLD deficiency causes auditory neuropathy due to reduced neurite outgrowth.Journal of clinical laboratory analysis · 2021Article
- Introducing the DizzyQuest: an app-based diary for vestibular disorders.Journal of neurology · 2020Article
- Electrical Vestibular Stimulation in Humans: A Narrative Review.Audiology & neuro-otology · 2020Review
- Pleiotrophin increases neurite length and number of spiral ganglion neurons in vitro.Experimental brain research · 2019Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
13 authors at 6 institutions in 5 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The peripheral vestibular system is critical for the execution of activities of daily life as it provides movement and orientation information to motor and sensory systems. Patients with bilateral vestibular hypofunction experience a significant decrease in quality of life and have currently no viable treatment option. Vestibular implants could eventually restore vestibular function. Most vestibular implant prototypes to date are modified cochlear implants to fast-track development. These use various objective measurements, such as the electrically evoked compound action potential (eCAP), to supplement behavioral information. We investigated whether eCAPs could be recorded in patients with a vestibulo-cochlear implant. Specifically, eCAPs were successfully recorded for cochlear and vestibular setups, as well as for mixed cochlear-vestibular setups. Similarities and slight differences were found for the recordings of the three setups. These findings demonstrated the feasibility of eCAP recording with a vestibulo-cochlear implant. They could be used in the short term to reduce current spread and avoid activation of non-targeted neurons. More research is warranted to better understand the neural origin of vestibular eCAPs and to utilize them for clinical applications.
Indexed as
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.